Abstract
BACKGROUND: The human papillomavirus (HPV) vaccine was conceived to prevent new HPV infections among uninfected young women. From the initial intentions, its use has been extended to older women and also tested as a therapeutic tool. We report two HPV vaccination outcomes during postconization follow-up. CASES: Two young women, with different clinical histories, were subjected to HPV vaccine after a loop electrosurgical excision procedure for high-grade cervical intraepithelial neoplasia (CIN) and persisting low-grade CIN. During follow-up both women experienced a worsening of cervical lesions, which resulted in invasive cervical cancer and severe dysplasia, respectively. CONCLUSION: Limited to our experience, a nonpersonalized HPV vaccine administration during postconization follow-up was expensive and unnecessary.
| Original language | English |
|---|---|
| Pages (from-to) | 455-457 |
| Number of pages | 3 |
| Journal | Journal of Reproductive Medicine for the Obstetrician and Gynecologist |
| Volume | 60 |
| Issue number | 5 |
| Publication status | Published - Oct 1 2015 |
Keywords
- Cervical cancer
- Cervical intraepithelial neoplasia
- Conization
- High-grade squamous intraepithelial lesions
- HPV vaccines
- HPV-16
- HSIL
- Human papillomavirus
- Human papillomavirus 16
- Human papillomavirus vaccines
- LEEP
- Loop electrosurgical excision procedure
- Uterine cervix
ASJC Scopus subject areas
- Obstetrics and Gynaecology
- Reproductive Medicine