Optical coherence tomography angiography of the peripapillary retina and optic nerve head in dominant optic atrophy.

N Balducci; A Ciardella; Roberto Gattegna; Q Zhou; ML Cascavilla; Chiara La Morgia; Giacomo Savini; Vincenzo Parisi; Francesco Bandello; Valerio Carelli; Piero Barboni

Optical coherence tomography angiography of the peripapillary retina and optic nerve head in dominant optic atrophy.

N Balducci, A Ciardella, Roberto Gattegna, Q Zhou, ML Cascavilla, Chiara La Morgia, Giacomo Savini, Vincenzo Parisi, Francesco Bandello, Valerio Carelli, Piero Barboni

Research output: Contribution to journal › Article › peer-review

Abstract

Peripapillar and nerve head vessel density (VD) was measured in 10 patients affected by Dominant optic atrophy (DOA) using optical coherence tomography angiography (OCT-A) and compared to the measurements of 15 age- and gender-matched controls. DOA patients showed VD reduction, mostly in the temporal and inferotemporal peripapillary sectors, according to the preferential involvement of the papillomacular bundle. Despite poor best-corrected visual acuity (BCVA), OCT-A revealed good repeatability. VD correlated with functional (mean deviation of visual field and BCVA) and structural (retinal nerve fiber layer thickness) parameters and could be a non-invasive, quantitative tool for the monitoring of the disease and of the therapeutic approaches

Original language	English
Article number	doi: 10.1016/j.mito.2017.03.002.
Pages (from-to)	60-65
Number of pages	6
Journal	Mitochondrion
Volume	36
Publication status	Published - Sept 2017

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@article{f9973baecef44a758d62b26829b2fba4,

title = "Optical coherence tomography angiography of the peripapillary retina and optic nerve head in dominant optic atrophy.",

abstract = "Peripapillar and nerve head vessel density (VD) was measured in 10 patients affected by Dominant optic atrophy (DOA) using optical coherence tomography angiography (OCT-A) and compared to the measurements of 15 age- and gender-matched controls. DOA patients showed VD reduction, mostly in the temporal and inferotemporal peripapillary sectors, according to the preferential involvement of the papillomacular bundle. Despite poor best-corrected visual acuity (BCVA), OCT-A revealed good repeatability. VD correlated with functional (mean deviation of visual field and BCVA) and structural (retinal nerve fiber layer thickness) parameters and could be a non-invasive, quantitative tool for the monitoring of the disease and of the therapeutic approaches",

author = "N Balducci and A Ciardella and Roberto Gattegna and Q Zhou and ML Cascavilla and {La Morgia}, Chiara and Giacomo Savini and Vincenzo Parisi and Francesco Bandello and Valerio Carelli and Piero Barboni",

year = "2017",

month = sep,

language = "English",

volume = "36",

pages = "60--65",

journal = "Mitochondrion",

issn = "1567-7249",

publisher = "Elsevier",

}

TY - JOUR

T1 - Optical coherence tomography angiography of the peripapillary retina and optic nerve head in dominant optic atrophy.

AU - Balducci, N

AU - Ciardella, A

AU - Gattegna, Roberto

AU - Zhou, Q

AU - Cascavilla, ML

AU - La Morgia, Chiara

AU - Savini, Giacomo

AU - Parisi, Vincenzo

AU - Bandello, Francesco

AU - Carelli, Valerio

AU - Barboni, Piero

PY - 2017/9

Y1 - 2017/9

N2 - Peripapillar and nerve head vessel density (VD) was measured in 10 patients affected by Dominant optic atrophy (DOA) using optical coherence tomography angiography (OCT-A) and compared to the measurements of 15 age- and gender-matched controls. DOA patients showed VD reduction, mostly in the temporal and inferotemporal peripapillary sectors, according to the preferential involvement of the papillomacular bundle. Despite poor best-corrected visual acuity (BCVA), OCT-A revealed good repeatability. VD correlated with functional (mean deviation of visual field and BCVA) and structural (retinal nerve fiber layer thickness) parameters and could be a non-invasive, quantitative tool for the monitoring of the disease and of the therapeutic approaches

AB - Peripapillar and nerve head vessel density (VD) was measured in 10 patients affected by Dominant optic atrophy (DOA) using optical coherence tomography angiography (OCT-A) and compared to the measurements of 15 age- and gender-matched controls. DOA patients showed VD reduction, mostly in the temporal and inferotemporal peripapillary sectors, according to the preferential involvement of the papillomacular bundle. Despite poor best-corrected visual acuity (BCVA), OCT-A revealed good repeatability. VD correlated with functional (mean deviation of visual field and BCVA) and structural (retinal nerve fiber layer thickness) parameters and could be a non-invasive, quantitative tool for the monitoring of the disease and of the therapeutic approaches

M3 - Article

SN - 1567-7249

VL - 36

SP - 60

EP - 65

JO - Mitochondrion

JF - Mitochondrion

M1 - doi: 10.1016/j.mito.2017.03.002.

ER -

Optical coherence tomography angiography of the peripapillary retina and optic nerve head in dominant optic atrophy.

Abstract

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