Olprinone, a PDE3 inhibitor, modulates the inflammation associated with myocardial ischemia-reperfusion injury in rats

Medicine & Life Sciences

• olprinone 100%
• Phosphodiesterase 3 Inhibitors 85%
• Myocardial Reperfusion Injury 70%
• Reperfusion Injury 53%
• Myocardial Ischemia 48%
• Inflammation 32%
• Reperfusion 28%
• Ischemia 24%
• Type 3 Cyclic Nucleotide Phosphodiesterases 16%
• Poly Adenosine Diphosphate Ribose 15%
• Uridine Triphosphate 14%
• 3-nitrotyrosine 14%
• Myocardial Reperfusion 13%
• Phosphodiesterase Inhibitors 13%
• P-Selectin 13%
• DNA Nucleotidylexotransferase 12%
• NF-kappa B 11%
• In Situ Nick-End Labeling 11%
• Vasodilator Agents 11%
• Interleukin-1 10%
• Constriction 10%
• Coronary Vessels 8%
• Anti-Inflammatory Agents 8%
• Tumor Necrosis Factor-alpha 7%
• Cytokines 6%
• Apoptosis 6%
• Blood Vessels 6%
• Wounds and Injuries 5%
• Pharmaceutical Preparations 4%
• Therapeutics 3%