Normalisation of CD4 counts in patients with HIV-1 infection and maximum virological suppression who are taking combination antiretroviral therapy: an observational cohort study

A. Mocroft; AN Phillips; J. Gatell; B. Ledergerber; M. Fisher; N. Clumeck; M. Losso; A. Lazzarin; G. Fatkenheuer; JD Lundgren

doi:10.1016/S0140-6736(07)60948-9

Normalisation of CD4 counts in patients with HIV-1 infection and maximum virological suppression who are taking combination antiretroviral therapy: an observational cohort study

A. Mocroft, AN Phillips, J. Gatell, B. Ledergerber, M. Fisher, N. Clumeck, M. Losso, A. Lazzarin, G. Fatkenheuer, JD Lundgren

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Combination antiretroviral therapy (cART) has been shown to reduce mortality and morbidity in patients with HIV. As viral replication falls, the CD4 count increases, but whether the CD4 count returns to the level seen in HIV-negative people is unknown. We aimed to assess whether the CD4 count for patients with maximum virological suppression (viral load

Original language	English
Pages (from-to)	407-413
Number of pages	7
Journal	Lancet
Volume	370
Issue number	9585
DOIs	https://doi.org/10.1016/S0140-6736(07)60948-9
Publication status	Published - Aug 4 2007

ASJC Scopus subject areas

Medicine(all)

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Mocroft, A., Phillips, AN., Gatell, J., Ledergerber, B., Fisher, M., Clumeck, N., Losso, M., Lazzarin, A., Fatkenheuer, G., & Lundgren, JD. (2007). Normalisation of CD4 counts in patients with HIV-1 infection and maximum virological suppression who are taking combination antiretroviral therapy: an observational cohort study. Lancet, 370(9585), 407-413. https://doi.org/10.1016/S0140-6736(07)60948-9

Mocroft, A, Phillips, AN, Gatell, J, Ledergerber, B, Fisher, M, Clumeck, N, Losso, M, Lazzarin, A, Fatkenheuer, G & Lundgren, JD 2007, 'Normalisation of CD4 counts in patients with HIV-1 infection and maximum virological suppression who are taking combination antiretroviral therapy: an observational cohort study', Lancet, vol. 370, no. 9585, pp. 407-413. https://doi.org/10.1016/S0140-6736(07)60948-9

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AU - Gatell, J.

AU - Ledergerber, B.

AU - Fisher, M.

AU - Clumeck, N.

AU - Losso, M.

AU - Lazzarin, A.

AU - Fatkenheuer, G.

AU - Lundgren, JD

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AB - Background: Combination antiretroviral therapy (cART) has been shown to reduce mortality and morbidity in patients with HIV. As viral replication falls, the CD4 count increases, but whether the CD4 count returns to the level seen in HIV-negative people is unknown. We aimed to assess whether the CD4 count for patients with maximum virological suppression (viral load

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Normalisation of CD4 counts in patients with HIV-1 infection and maximum virological suppression who are taking combination antiretroviral therapy: an observational cohort study

Abstract

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