Protocollo diagnostico "non invasivo" ed approccio chirurgico nell'epilessia temporale farmacoresistente

P. P. Quarato; G. Di Gennaro; V. Esposito; L. G. Grammaldo; N. G. Meldolesi; G. B. Colazza; A. Mascia; F. Mari; G. Cantore; M. Manfredi

Protocollo diagnostico "non invasivo" ed approccio chirurgico nell'epilessia temporale farmacoresistente

Translated title of the contribution: Non invasive pre-surgical evaluation and surgery in drug-resistant temporal lobe epilepsy

P. P. Quarato, G. Di Gennaro, V. Esposito, L. G. Grammaldo, N. G. Meldolesi, G. B. Colazza, A. Mascia, F. Mari, G. Cantore, M. Manfredi

www.neuromed.it

Research output: Contribution to journal › Article › peer-review

Abstract

About 30 % of patients affected by partial epilepsy are not well controlled by AED therapy and have disabling seizures. In well selected patients, epilepsy surgery may constitute an useful therapeutical approach. Drug-resistant temporal lobe epilepsy is considered an epileptic syndrome in wich surgery is very effective in controlling seizures. The Epilepsy Surgery Unit of "Neuromed" Institute in Pozzilli (IS) began his activity three years ago. At this time 65 patient affected by drug-resistant temporal lobe epilepsy, selected by means of non invasive diagnostic protocol (Long term Video-EEG monitoring, MRI and CT scans of the brain, neuropsychologic and psychiatric evaluation, Wada test in well selected cases) underwent neurosurgery: at follow-up (<1 year in 29 patients) 92 % of patients was seizure-free. Sixty one patients with unclear epileptogenic zone were scheduled for invasive investigations (stereo-EEG).

Translated title of the contribution	Non invasive pre-surgical evaluation and surgery in drug-resistant temporal lobe epilepsy
Original language	Italian
Pages (from-to)	151-154
Number of pages	4
Journal	Bollettino - Lega Italiana contro l'Epilessia
Issue number	118
Publication status	Published - Oct 2002

ASJC Scopus subject areas

Clinical Neurology

Cite this

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title = "Protocollo diagnostico {"}non invasivo{"} ed approccio chirurgico nell'epilessia temporale farmacoresistente",

abstract = "About 30 % of patients affected by partial epilepsy are not well controlled by AED therapy and have disabling seizures. In well selected patients, epilepsy surgery may constitute an useful therapeutical approach. Drug-resistant temporal lobe epilepsy is considered an epileptic syndrome in wich surgery is very effective in controlling seizures. The Epilepsy Surgery Unit of {"}Neuromed{"} Institute in Pozzilli (IS) began his activity three years ago. At this time 65 patient affected by drug-resistant temporal lobe epilepsy, selected by means of non invasive diagnostic protocol (Long term Video-EEG monitoring, MRI and CT scans of the brain, neuropsychologic and psychiatric evaluation, Wada test in well selected cases) underwent neurosurgery: at follow-up (<1 year in 29 patients) 92 % of patients was seizure-free. Sixty one patients with unclear epileptogenic zone were scheduled for invasive investigations (stereo-EEG).",

keywords = "Epilepsy Surgery, Presurgical Evaluation, Temporal Lobe Epilepsy, Video-EEG",

author = "Quarato, {P. P.} and {Di Gennaro}, G. and V. Esposito and Grammaldo, {L. G.} and Meldolesi, {N. G.} and Colazza, {G. B.} and A. Mascia and F. Mari and G. Cantore and M. Manfredi",

year = "2002",

month = oct,

language = "Italian",

pages = "151--154",

journal = "Bollettino - Lega Italiana contro l'Epilessia",

issn = "0394-560X",

publisher = "Lega Italiana contro l'Epilessia",

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T1 - Protocollo diagnostico "non invasivo" ed approccio chirurgico nell'epilessia temporale farmacoresistente

AU - Quarato, P. P.

AU - Di Gennaro, G.

AU - Esposito, V.

AU - Grammaldo, L. G.

AU - Meldolesi, N. G.

AU - Colazza, G. B.

AU - Mascia, A.

AU - Mari, F.

AU - Cantore, G.

AU - Manfredi, M.

PY - 2002/10

Y1 - 2002/10

N2 - About 30 % of patients affected by partial epilepsy are not well controlled by AED therapy and have disabling seizures. In well selected patients, epilepsy surgery may constitute an useful therapeutical approach. Drug-resistant temporal lobe epilepsy is considered an epileptic syndrome in wich surgery is very effective in controlling seizures. The Epilepsy Surgery Unit of "Neuromed" Institute in Pozzilli (IS) began his activity three years ago. At this time 65 patient affected by drug-resistant temporal lobe epilepsy, selected by means of non invasive diagnostic protocol (Long term Video-EEG monitoring, MRI and CT scans of the brain, neuropsychologic and psychiatric evaluation, Wada test in well selected cases) underwent neurosurgery: at follow-up (<1 year in 29 patients) 92 % of patients was seizure-free. Sixty one patients with unclear epileptogenic zone were scheduled for invasive investigations (stereo-EEG).

AB - About 30 % of patients affected by partial epilepsy are not well controlled by AED therapy and have disabling seizures. In well selected patients, epilepsy surgery may constitute an useful therapeutical approach. Drug-resistant temporal lobe epilepsy is considered an epileptic syndrome in wich surgery is very effective in controlling seizures. The Epilepsy Surgery Unit of "Neuromed" Institute in Pozzilli (IS) began his activity three years ago. At this time 65 patient affected by drug-resistant temporal lobe epilepsy, selected by means of non invasive diagnostic protocol (Long term Video-EEG monitoring, MRI and CT scans of the brain, neuropsychologic and psychiatric evaluation, Wada test in well selected cases) underwent neurosurgery: at follow-up (<1 year in 29 patients) 92 % of patients was seizure-free. Sixty one patients with unclear epileptogenic zone were scheduled for invasive investigations (stereo-EEG).

KW - Epilepsy Surgery

KW - Presurgical Evaluation

KW - Temporal Lobe Epilepsy

KW - Video-EEG

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M3 - Articolo

AN - SCOPUS:0036820865

SN - 0394-560X

SP - 151

EP - 154

JO - Bollettino - Lega Italiana contro l'Epilessia

JF - Bollettino - Lega Italiana contro l'Epilessia

IS - 118

ER -

Protocollo diagnostico "non invasivo" ed approccio chirurgico nell'epilessia temporale farmacoresistente

Abstract

ASJC Scopus subject areas

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