Non-invasive mechanical ventilation in critically Ill Trauma patients: A systematic review

Annia Schreiber, Fatma Yıldırım, Giovanni Ferrari, Andrea Antonelli, Pablo Bayoumy Delis, Murat Gündüz, Marcin Karcz, Peter Papadakos, Roberto Cosentini, Yalım Dikmen, Antonio M. Esquinas

Research output: Contribution to journalReview articlepeer-review


There is limited literature on non-invasive mechanical ventilation (NIMV) in patients with polytrauma-related acute respiratory failure (ARF). Despite an increasing worldwide application, there is still scarce evidence of significant NIMV benefits in this specific setting, and no clear recommendations are provided. We performed a systematic review, and a search of clinical databases including MEDLINE and EMBASE was conducted from the beginning of 1990 until today. Although the benefits in reducing the intubation rate, morbidity and mortality are unclear, NIMV may be useful and does not appear to be associated with harm when applied in properly selected patients with moderate ARF at an earlier stage of injury by experienced teams and in appropriate settings under strict monitoring. In the presence of these criteria, NIMV is worth attempting, but only if endotracheal intubation is promptly available because non-responders to NIMV are burdened by an increased mortality when intubation is delayed.

Original languageEnglish
Pages (from-to)88-95
Number of pages8
JournalTurk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
Issue number2
Publication statusPublished - Jan 1 2018


  • Acute lung injury
  • Acute respiratory distress syndrome
  • Acute respiratory failure
  • Continuous positive airway pressure
  • Non-invasive mechanical ventilation
  • Transfusion-associated circulatory overload

ASJC Scopus subject areas

  • Emergency Medicine
  • Anesthesiology and Pain Medicine


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