TY - JOUR
T1 - Trapianto di rene da donatore a cuore non battente
T2 - la prima esperienza in Italia.
AU - Rampino, Teresa
AU - Abelli, Massimo
AU - Ticozzelli, Elena
AU - Gregorini, Marilena
AU - Bosio, Francesca
AU - Piotti, Giovanni
AU - Bedino, Giulia
AU - Esposito, Pasquale
AU - Balenzano, Chiara Teresa
AU - Geraci, Paolo
AU - Dal Canton, Antonio
PY - 2010/1
Y1 - 2010/1
N2 - A promising way to increase the number of kidneys for transplantation is to expand the donor pool by including non-heart-beating donors (NHBDs). The centers involved in NHBD transplantation programs have reported a 16-40% increase in kidney transplants. A key issue with NHBD is the significantly higher rate of delayed graft function (DGF) and primary non-function (PNF) compared with that associated with heart-beating donor (HBD) transplants. However, although transplants from NHBD are associated with a greater incidence of early adverse events, long-term graft survival appears to be similar to that observed after transplants from HBDs. In addition, the use of extracorporeal membrane oxygenation and mechanical perfusion, the careful selection of recipients and donors, and an adequate therapeutic strategy may at least partially reduce the risk of PNF and DGF and improve transplant outcome.
AB - A promising way to increase the number of kidneys for transplantation is to expand the donor pool by including non-heart-beating donors (NHBDs). The centers involved in NHBD transplantation programs have reported a 16-40% increase in kidney transplants. A key issue with NHBD is the significantly higher rate of delayed graft function (DGF) and primary non-function (PNF) compared with that associated with heart-beating donor (HBD) transplants. However, although transplants from NHBD are associated with a greater incidence of early adverse events, long-term graft survival appears to be similar to that observed after transplants from HBDs. In addition, the use of extracorporeal membrane oxygenation and mechanical perfusion, the careful selection of recipients and donors, and an adequate therapeutic strategy may at least partially reduce the risk of PNF and DGF and improve transplant outcome.
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M3 - Articolo
C2 - 20191461
AN - SCOPUS:77952514003
SN - 0393-5590
VL - 27
SP - 56
EP - 68
JO - Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia
JF - Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia
IS - 1
ER -