TY - JOUR
T1 - Non-healing post-surgical fistulae
T2 - treatment with image-guided percutaneous injection of cyanoacrylic glue
AU - Mauri, Giovanni
AU - Pescatori, Lorenzo C.
AU - Mattiuz, Chiara
AU - Poretti, Dario
AU - Pedicini, Vittorio
AU - Melchiorre, Fabio
AU - Rossi, Umberto
AU - Solbiati, Luigi
AU - Sconfienza, Luca Maria
PY - 2016/10/17
Y1 - 2016/10/17
N2 - Objectives: To present the results of our experience with cyanoacrylic glue percutaneous injection to treat post-surgical non-healing enteric fistulae after failure of standard treatments. Methods: Eighteen patients (14 males; age range 33–84, mean 69 years) were treated for a non-healing post-surgical enteric fistula after failure of standard treatments. Under computed tomography and/or fluoroscopic guidance, a mixture of cyanoacrylic glue (Glubran 2, GEM, Viareggio, Italy) and ethiodized oil was injected at the site of the fistula. Fistula was considered healed when no material was drained by the percutaneous drainage and a subsequent computed tomography confirmed the disappearance of any fluid collection. Results: In all cases, it was possible to reach the site of the fistula using a percutaneous access. A median of 1 injection (range 1–5) was performed. Fistula healing was achieved in 16/18 (89 %) patients. One patient died for other reasons before fistula healing. Median time for fistula healing was 0 days (mean 8, range 0–58 days). No complications occurred. Reoperation was needed in one patient. Conclusions: Percutaneous injection of cyanoacrylic glue is feasible, safe, and effective to treat non-healing post-surgical enteric fistulae. It may represent a further option to avoid surgical reoperation in frail patients.
AB - Objectives: To present the results of our experience with cyanoacrylic glue percutaneous injection to treat post-surgical non-healing enteric fistulae after failure of standard treatments. Methods: Eighteen patients (14 males; age range 33–84, mean 69 years) were treated for a non-healing post-surgical enteric fistula after failure of standard treatments. Under computed tomography and/or fluoroscopic guidance, a mixture of cyanoacrylic glue (Glubran 2, GEM, Viareggio, Italy) and ethiodized oil was injected at the site of the fistula. Fistula was considered healed when no material was drained by the percutaneous drainage and a subsequent computed tomography confirmed the disappearance of any fluid collection. Results: In all cases, it was possible to reach the site of the fistula using a percutaneous access. A median of 1 injection (range 1–5) was performed. Fistula healing was achieved in 16/18 (89 %) patients. One patient died for other reasons before fistula healing. Median time for fistula healing was 0 days (mean 8, range 0–58 days). No complications occurred. Reoperation was needed in one patient. Conclusions: Percutaneous injection of cyanoacrylic glue is feasible, safe, and effective to treat non-healing post-surgical enteric fistulae. It may represent a further option to avoid surgical reoperation in frail patients.
KW - Cyanoacrilyc glue
KW - Enteric fistula
KW - Glubran
KW - Image-guided technique
KW - Percutaneous treatment
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U2 - 10.1007/s11547-016-0693-7
DO - 10.1007/s11547-016-0693-7
M3 - Article
AN - SCOPUS:84991661320
SN - 0033-8362
SP - 1
EP - 7
JO - Radiologia Medica
JF - Radiologia Medica
ER -