Nocturnal hypertension and right heart remodeling

Marijana Tadic, Cesare Cuspidi, Vera Celic, Biljana Pencic-Popovic, Giuseppe Mancia

Research output: Contribution to journalArticlepeer-review


Background: We sought to investigate right ventricular (RV) and right atrial mechanics in patients with daytime, night-Time and daytime-night-Time hypertension. Methods: This cross-sectional study included 256 untreated patients who underwent 24-h ambulatory blood pressure monitoring and complete echocardiographic examination including strain analysis. Night-Time hypertension was defined as nocturnal SBP at least 120mmHg and/or DBP at least 70mmHg and daytime hypertension as SBP at least 135mmHg and/or DBP at least 85mmHg. Results: RV structure, diastolic function and global longitudinal RV strain in patients with nocturnal hypertension are intermediate between daytime and daytime-night-Time hypertension. On the other side, RV systolic and diastolic strain rates referring to the RV free wall are significantly deteriorated in the patients with nocturnal and daytime-night-Time hypertension in comparison with normotension and daytime hypertension. Right atrial conduit function is significantly reduced in the patients with nocturnal and day-night-Time hypertension comparing with other two groups, whereas right atrial reservoir and pump functions are intermediate between daytime and daytime-night-Time hypertension. A 24-h SBP is independently of other clinical and echocardiographic parameters associated with RV and right atrial global strain. Conclusion: RV mechanics is worse in night-Time and daytime-night-Time hypertensive patients than in normotensive controls and isolated daytime hypertensive patients. A 24-h SBP is independently associated with right heart mechanics.

Original languageEnglish
Pages (from-to)136-142
Number of pages7
JournalJournal of Hypertension
Issue number1
Publication statusPublished - Jan 1 2018


  • 24-h blood pressure monitoring
  • nocturnal hypertension
  • right atrium
  • right ventricle
  • speckle tracking imaging

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine


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