Need for High Radiation Dose (≥70 Gy) in Early Postoperative Irradiation After Radical Prostatectomy: A Single-Institution Analysis of 334 High-Risk, Node-Negative Patients

Cesare Cozzarini; Francesco Montorsi; Claudio Fiorino; Filippo Alongi; Angelo Bolognesi; Luigi Filippo Da Pozzo; Giorgio Guazzoni; Massimo Freschi; Marco Roscigno; Vincenzo Scattoni; Patrizio Rigatti; Nadia Di Muzio

doi:10.1016/j.ijrobp.2008.12.059

Need for High Radiation Dose (≥70 Gy) in Early Postoperative Irradiation After Radical Prostatectomy: A Single-Institution Analysis of 334 High-Risk, Node-Negative Patients

Cesare Cozzarini, Francesco Montorsi, Claudio Fiorino, Filippo Alongi, Angelo Bolognesi, Luigi Filippo Da Pozzo, Giorgio Guazzoni, Massimo Freschi, Marco Roscigno, Vincenzo Scattoni, Patrizio Rigatti, Nadia Di Muzio

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: To determine the clinical benefit of high-dose early adjuvant radiotherapy (EART) in high-risk prostate cancer (hrCaP) patients submitted to radical retropubic prostatectomy plus pelvic lymphadenectomy. Patients and Methods: The clinical outcome of 334 hrCaP (pT3-4 and/or positive resection margins) node-negative patients submitted to radical retropubic prostatectomy plus pelvic lymphadenectomy before 2004 was analyzed according to the EART dose delivered to the prostatic bed,

Original language	English
Pages (from-to)	966-974
Number of pages	9
Journal	International Journal of Radiation Oncology Biology Physics
Volume	75
Issue number	4
DOIs	https://doi.org/10.1016/j.ijrobp.2008.12.059
Publication status	Published - Nov 15 2009

Keywords

Adjuvant
Dose
Prostatectomy
Prostatic neoplasms
Radiotherapy

ASJC Scopus subject areas

Cancer Research
Oncology
Radiology Nuclear Medicine and imaging
Radiation

Access to Document

10.1016/j.ijrobp.2008.12.059

Cite this

Cozzarini, C., Montorsi, F., Fiorino, C., Alongi, F., Bolognesi, A., Da Pozzo, L. F., Guazzoni, G., Freschi, M., Roscigno, M., Scattoni, V., Rigatti, P., & Di Muzio, N. (2009). Need for High Radiation Dose (≥70 Gy) in Early Postoperative Irradiation After Radical Prostatectomy: A Single-Institution Analysis of 334 High-Risk, Node-Negative Patients. International Journal of Radiation Oncology Biology Physics, 75(4), 966-974. https://doi.org/10.1016/j.ijrobp.2008.12.059

Need for High Radiation Dose (≥70 Gy) in Early Postoperative Irradiation After Radical Prostatectomy : A Single-Institution Analysis of 334 High-Risk, Node-Negative Patients. / Cozzarini, Cesare ; Montorsi, Francesco ; Fiorino, Claudio et al.

In: International Journal of Radiation Oncology Biology Physics, Vol. 75, No. 4, 15.11.2009, p. 966-974.

Research output: Contribution to journal › Article › peer-review

Cozzarini, C , Montorsi, F , Fiorino, C, Alongi, F, Bolognesi, A, Da Pozzo, LF, Guazzoni, G, Freschi, M, Roscigno, M, Scattoni, V, Rigatti, P & Di Muzio, N 2009, 'Need for High Radiation Dose (≥70 Gy) in Early Postoperative Irradiation After Radical Prostatectomy: A Single-Institution Analysis of 334 High-Risk, Node-Negative Patients', International Journal of Radiation Oncology Biology Physics, vol. 75, no. 4, pp. 966-974. https://doi.org/10.1016/j.ijrobp.2008.12.059

Cozzarini C , Montorsi F , Fiorino C, Alongi F, Bolognesi A, Da Pozzo LF et al. Need for High Radiation Dose (≥70 Gy) in Early Postoperative Irradiation After Radical Prostatectomy: A Single-Institution Analysis of 334 High-Risk, Node-Negative Patients. International Journal of Radiation Oncology Biology Physics. 2009 Nov 15;75(4):966-974. doi: 10.1016/j.ijrobp.2008.12.059

@article{a61152d22d1b401bb42251718b55a2d3,

title = "Need for High Radiation Dose (≥70 Gy) in Early Postoperative Irradiation After Radical Prostatectomy: A Single-Institution Analysis of 334 High-Risk, Node-Negative Patients",

abstract = "Purpose: To determine the clinical benefit of high-dose early adjuvant radiotherapy (EART) in high-risk prostate cancer (hrCaP) patients submitted to radical retropubic prostatectomy plus pelvic lymphadenectomy. Patients and Methods: The clinical outcome of 334 hrCaP (pT3-4 and/or positive resection margins) node-negative patients submitted to radical retropubic prostatectomy plus pelvic lymphadenectomy before 2004 was analyzed according to the EART dose delivered to the prostatic bed, ",

keywords = "Adjuvant, Dose, Prostatectomy, Prostatic neoplasms, Radiotherapy",

author = "Cesare Cozzarini and Francesco Montorsi and Claudio Fiorino and Filippo Alongi and Angelo Bolognesi and {Da Pozzo}, {Luigi Filippo} and Giorgio Guazzoni and Massimo Freschi and Marco Roscigno and Vincenzo Scattoni and Patrizio Rigatti and {Di Muzio}, Nadia",

year = "2009",

month = nov,

day = "15",

doi = "10.1016/j.ijrobp.2008.12.059",

language = "English",

volume = "75",

pages = "966--974",

journal = "International Journal of Radiation Oncology Biology Physics",

issn = "0360-3016",

publisher = "Elsevier Inc.",

number = "4",

}

TY - JOUR

T1 - Need for High Radiation Dose (≥70 Gy) in Early Postoperative Irradiation After Radical Prostatectomy

T2 - A Single-Institution Analysis of 334 High-Risk, Node-Negative Patients

AU - Cozzarini, Cesare

AU - Montorsi, Francesco

AU - Fiorino, Claudio

AU - Alongi, Filippo

AU - Bolognesi, Angelo

AU - Da Pozzo, Luigi Filippo

AU - Guazzoni, Giorgio

AU - Freschi, Massimo

AU - Roscigno, Marco

AU - Scattoni, Vincenzo

AU - Rigatti, Patrizio

AU - Di Muzio, Nadia

PY - 2009/11/15

Y1 - 2009/11/15

N2 - Purpose: To determine the clinical benefit of high-dose early adjuvant radiotherapy (EART) in high-risk prostate cancer (hrCaP) patients submitted to radical retropubic prostatectomy plus pelvic lymphadenectomy. Patients and Methods: The clinical outcome of 334 hrCaP (pT3-4 and/or positive resection margins) node-negative patients submitted to radical retropubic prostatectomy plus pelvic lymphadenectomy before 2004 was analyzed according to the EART dose delivered to the prostatic bed,

AB - Purpose: To determine the clinical benefit of high-dose early adjuvant radiotherapy (EART) in high-risk prostate cancer (hrCaP) patients submitted to radical retropubic prostatectomy plus pelvic lymphadenectomy. Patients and Methods: The clinical outcome of 334 hrCaP (pT3-4 and/or positive resection margins) node-negative patients submitted to radical retropubic prostatectomy plus pelvic lymphadenectomy before 2004 was analyzed according to the EART dose delivered to the prostatic bed,

KW - Adjuvant

KW - Dose

KW - Prostatectomy

KW - Prostatic neoplasms

KW - Radiotherapy

UR - http://www.scopus.com/inward/record.url?scp=70350781901&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70350781901&partnerID=8YFLogxK

U2 - 10.1016/j.ijrobp.2008.12.059

DO - 10.1016/j.ijrobp.2008.12.059

M3 - Article

C2 - 19619960

AN - SCOPUS:70350781901

SN - 0360-3016

VL - 75

SP - 966

EP - 974

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

IS - 4

ER -

Need for High Radiation Dose (≥70 Gy) in Early Postoperative Irradiation After Radical Prostatectomy: A Single-Institution Analysis of 334 High-Risk, Node-Negative Patients

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this