Abstract
A novel type of carbapenemase, New Delhi metallo β- lactamase-1 (NDM-1), was first identified in 2008 in two Enterobacteriacea isolates, both recovered from a Swedish patient transferred from India. The emergence of NDM-1 is now reported from all continents, often in patients with a history of travel or hospitalization in the Indian subcontinent. The NDM-1 producing Gram-negative bacteria are mainly Enterobacteriaceae, which can cause colonization or fatal infections, with worrying antimicrobial susceptibility profiles: some isolates have developed resistance to practically all available antibiotics. Is the NDM-1 the super-bug? Are we in the post-antibiotic era? This review is a summary of currently available knowledge of NDM-1 that draws attention to future antimicrobial resistance scenarios.
| Translated title of the contribution | NDM-1: The superbug? |
|---|---|
| Original language | Italian |
| Pages (from-to) | 224-234 |
| Number of pages | 11 |
| Journal | Infezioni in Medicina |
| Volume | 19 |
| Issue number | 4 |
| Publication status | Published - Dec 2011 |
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases