MOF in gravida pretermine: gestosi e/o febbre tifoidea?

Translated title of the contribution: Multiple organ failure in pre-term pregnancy: gestosis and/or typhoid fever?

C. Iermano, M. Giurbino, F. Aloj, G. Servillo, M. Pezza

Research output: Contribution to journalArticlepeer-review


The authors describe a clinical case of Multiple Organ Failure (MOF). Such a pathology was reported, at admission in ICU, in a young woman aged 26 who was in the 30th week of amenorrhoea, formerly hospitalized in Obstetrics, where she had had a Caesarean section because of the met of eclamptic crisis, after a pregnancy substantially normal. At the moment of her admission to the ICU the examination highlighted the sense organ obnubilated, the breath dyspnoic, a systolic and diastolic hypotension and a tachycardia of medium seriousness. From laboratory examinations it was possible to maintain that there was a serious anemia with white cells raised, a coagulative imbalance and above all a serious alteration of hepatic and pancreatic function. The creatininemia had increased a bit, a clear contraction of diuresis was present and a considerable metabolic acidosis had become intelled. Therefore the patient was affected by multiple organ failure. In successive days it was possible to execute an EEG that proved substantially normal, then a Computer Tomography to abdomen showed the presence of vast areas of hepatic necrosis, ascitic hemorrhagic fluid and a volume increased pancreas. Hepatitis markers proved negative, while a positive response was achieved for a typhoid infection (this result was reconfirmed many times later.) Modifying the antibiotic therapy (substituting full dose ampicillin to the cephalosporin) the clinical case was solved. Moreover, also thanks to a very good answer to antibiotic therapy, it was possible to confirm the diagnosis of typhoid fever, not gestosis.

Translated title of the contributionMultiple organ failure in pre-term pregnancy: gestosis and/or typhoid fever?
Original languageItalian
Pages (from-to)341-344
Number of pages4
JournalMinerva Anestesiologica
Issue number6
Publication statusPublished - Jun 1994

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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