Motor nerve biopsy: Clinical usefulness and histopathological criteria

Nilo Riva; Sandro Iannaccone; Massimo Corbo; Chiara Casellato; Barbara Sferrazza; Alberto Lazzerini; Marina Scarlato; Federica Cerri; Stefano C. Previtali; Eduardo Nobile-Orazio; Giancarlo Comi; Angelo Quattrini

doi:10.1002/ana.22110

Motor nerve biopsy: Clinical usefulness and histopathological criteria

Nilo Riva, Sandro Iannaccone, Massimo Corbo, Chiara Casellato, Barbara Sferrazza, Alberto Lazzerini, Marina Scarlato, Federica Cerri, Stefano C. Previtali, Eduardo Nobile-Orazio, Giancarlo Comi, Angelo Quattrini

Research output: Contribution to journal › Article › peer-review

Abstract

Early differential diagnosis of motor neuropathies (MN) and lower motor neuron diseases (LMND) is important, as prognosis and therapeutic approaches are different. We evaluated the diagnostic contribution of the biopsy of the motor branch of the obturator nerve and gracilis muscle in 21 consecutive patients in which, after proper clinical and neurophysiological studies, the differential diagnosis was still open. At baseline, motor biopsy was performed; diagnostic confirmation was obtained by 2-year clinical follow-up. Our results support the usefulness of this diagnostic procedure for selected cases of MN and LMND.

Original language	English
Pages (from-to)	197-201
Number of pages	5
Journal	Annals of Neurology
Volume	69
Issue number	1
DOIs	https://doi.org/10.1002/ana.22110
Publication status	Published - Jan 2011

ASJC Scopus subject areas

Neurology
Clinical Neurology

Access to Document

10.1002/ana.22110

Cite this

@article{bdf7d20e822e4283ad3320ea9e99589b,

title = "Motor nerve biopsy: Clinical usefulness and histopathological criteria",

abstract = "Early differential diagnosis of motor neuropathies (MN) and lower motor neuron diseases (LMND) is important, as prognosis and therapeutic approaches are different. We evaluated the diagnostic contribution of the biopsy of the motor branch of the obturator nerve and gracilis muscle in 21 consecutive patients in which, after proper clinical and neurophysiological studies, the differential diagnosis was still open. At baseline, motor biopsy was performed; diagnostic confirmation was obtained by 2-year clinical follow-up. Our results support the usefulness of this diagnostic procedure for selected cases of MN and LMND.",

author = "Nilo Riva and Sandro Iannaccone and Massimo Corbo and Chiara Casellato and Barbara Sferrazza and Alberto Lazzerini and Marina Scarlato and Federica Cerri and Previtali, {Stefano C.} and Eduardo Nobile-Orazio and Giancarlo Comi and Angelo Quattrini",

year = "2011",

month = jan,

doi = "10.1002/ana.22110",

language = "English",

volume = "69",

pages = "197--201",

journal = "Annals of Neurology",

issn = "0364-5134",

publisher = "John Wiley and Sons Inc.",

number = "1",

}

TY - JOUR

T1 - Motor nerve biopsy

T2 - Clinical usefulness and histopathological criteria

AU - Riva, Nilo

AU - Iannaccone, Sandro

AU - Corbo, Massimo

AU - Casellato, Chiara

AU - Sferrazza, Barbara

AU - Lazzerini, Alberto

AU - Scarlato, Marina

AU - Cerri, Federica

AU - Previtali, Stefano C.

AU - Nobile-Orazio, Eduardo

AU - Comi, Giancarlo

AU - Quattrini, Angelo

PY - 2011/1

Y1 - 2011/1

N2 - Early differential diagnosis of motor neuropathies (MN) and lower motor neuron diseases (LMND) is important, as prognosis and therapeutic approaches are different. We evaluated the diagnostic contribution of the biopsy of the motor branch of the obturator nerve and gracilis muscle in 21 consecutive patients in which, after proper clinical and neurophysiological studies, the differential diagnosis was still open. At baseline, motor biopsy was performed; diagnostic confirmation was obtained by 2-year clinical follow-up. Our results support the usefulness of this diagnostic procedure for selected cases of MN and LMND.

AB - Early differential diagnosis of motor neuropathies (MN) and lower motor neuron diseases (LMND) is important, as prognosis and therapeutic approaches are different. We evaluated the diagnostic contribution of the biopsy of the motor branch of the obturator nerve and gracilis muscle in 21 consecutive patients in which, after proper clinical and neurophysiological studies, the differential diagnosis was still open. At baseline, motor biopsy was performed; diagnostic confirmation was obtained by 2-year clinical follow-up. Our results support the usefulness of this diagnostic procedure for selected cases of MN and LMND.

UR - http://www.scopus.com/inward/record.url?scp=79551502361&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79551502361&partnerID=8YFLogxK

U2 - 10.1002/ana.22110

DO - 10.1002/ana.22110

M3 - Article

C2 - 21280090

AN - SCOPUS:79551502361

SN - 0364-5134

VL - 69

SP - 197

EP - 201

JO - Annals of Neurology

JF - Annals of Neurology

IS - 1

ER -

Motor nerve biopsy: Clinical usefulness and histopathological criteria

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this