Morpho-structural investigations of biomaterials for biocidal activity

A. Pugnaloni; F. Gabbanelli; M. Mattioli-Belmonte; A. Delfino; G. Biagini; M. G. Tucci; G. Ricotti; F. Orlando; C. Viticchi; M. Fini

doi:10.1177/088391102031641

Morpho-structural investigations of biomaterials for biocidal activity

A. Pugnaloni, F. Gabbanelli, M. Mattioli-Belmonte, A. Delfino, G. Biagini, M. G. Tucci, G. Ricotti, F. Orlando, C. Viticchi, M. Fini

Research output: Contribution to journal › Article › peer-review

Abstract

A new wound dressing made of gelatin and Ag, was evaluated for the management of tissue reconstitution in rats. The gelatin-based dressing, with metabolic stimulation properties that favored the recovery of the skin was made of stiff sheets to supply the repairing tissue with mechanical support. The gelatin sheets enhanced the development of collagen fibers and subsequently cell proliferation at the level of stromal and vascular elements. A protocol based on the utilization of natural biomaterials in the presence of low concentrations of a biocidal was proposed which could control microbiocidal activities principally in burned and debilitated patients.

Original language	English
Pages (from-to)	451-462
Number of pages	12
Journal	Journal of Bioactive and Compatible Polymers
Volume	17
Issue number	6
DOIs	https://doi.org/10.1177/088391102031641
Publication status	Published - Nov 2002

Keywords

Biocides
Biomaterials
Collagen
Cutaneous repair
Gelatin
Wound dressing

ASJC Scopus subject areas

Biotechnology
Biomaterials
Polymers and Plastics
Materials Chemistry

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10.1177/088391102031641

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title = "Morpho-structural investigations of biomaterials for biocidal activity",

abstract = "A new wound dressing made of gelatin and Ag, was evaluated for the management of tissue reconstitution in rats. The gelatin-based dressing, with metabolic stimulation properties that favored the recovery of the skin was made of stiff sheets to supply the repairing tissue with mechanical support. The gelatin sheets enhanced the development of collagen fibers and subsequently cell proliferation at the level of stromal and vascular elements. A protocol based on the utilization of natural biomaterials in the presence of low concentrations of a biocidal was proposed which could control microbiocidal activities principally in burned and debilitated patients.",

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T1 - Morpho-structural investigations of biomaterials for biocidal activity

AU - Pugnaloni, A.

AU - Gabbanelli, F.

AU - Mattioli-Belmonte, M.

AU - Delfino, A.

AU - Biagini, G.

AU - Tucci, M. G.

AU - Ricotti, G.

AU - Orlando, F.

AU - Viticchi, C.

AU - Fini, M.

PY - 2002/11

Y1 - 2002/11

N2 - A new wound dressing made of gelatin and Ag, was evaluated for the management of tissue reconstitution in rats. The gelatin-based dressing, with metabolic stimulation properties that favored the recovery of the skin was made of stiff sheets to supply the repairing tissue with mechanical support. The gelatin sheets enhanced the development of collagen fibers and subsequently cell proliferation at the level of stromal and vascular elements. A protocol based on the utilization of natural biomaterials in the presence of low concentrations of a biocidal was proposed which could control microbiocidal activities principally in burned and debilitated patients.

AB - A new wound dressing made of gelatin and Ag, was evaluated for the management of tissue reconstitution in rats. The gelatin-based dressing, with metabolic stimulation properties that favored the recovery of the skin was made of stiff sheets to supply the repairing tissue with mechanical support. The gelatin sheets enhanced the development of collagen fibers and subsequently cell proliferation at the level of stromal and vascular elements. A protocol based on the utilization of natural biomaterials in the presence of low concentrations of a biocidal was proposed which could control microbiocidal activities principally in burned and debilitated patients.

KW - Biocides

KW - Biomaterials

KW - Collagen

KW - Cutaneous repair

KW - Gelatin

KW - Wound dressing

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JF - Journal of Bioactive and Compatible Polymers

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Morpho-structural investigations of biomaterials for biocidal activity

Abstract

Keywords

ASJC Scopus subject areas

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