Monoclonal antibodies by genetic engineering: Novel reagents for in vivo diagnosis and therapy

S. Canevari, D. Furlan, A. Mossa, M. Figini

Research output: Contribution to journalArticlepeer-review

Abstract

In only a few years, the technology of antibody engineering has demonstrated its power and a variety of recombinant monoclonal antibodies are now being developed. Recent developments in gene manipulation have allowed the isolation of antibodies, including human antibodies, with or without immunization, by displaying functional antibody fragments on the surface of bacteriophage particles and directly selecting with antigen. In the present review some recent achievements in these areas are highlighted.

Original languageEnglish
Pages (from-to)147-150
Number of pages4
JournalInternational Journal of Biological Markers
Volume8
Issue number3
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Biochemistry
  • Immunology

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