TY - JOUR
T1 - Molecular detection of gastrointestinal viral infections in hospitalized patients
AU - Rovida, Francesca
AU - Campanini, Giulia
AU - Piralla, Antonio
AU - Adzasehoun, Kodjo Messan Guy
AU - Sarasini, Antonella
AU - Baldanti, Fausto
PY - 2013/11
Y1 - 2013/11
N2 - Gastrointestinal viral syndromes are a common cause of morbidity and mortality in humans worldwide. Etiological agents include a large number of viruses encompassing several orders, families, and genera. During the period April 2011 to April 2012, 689 stool samples from as many patients hospitalized at the Fondazione IRCCS Policlinico San Matteo of Pavia exhibiting gastrointestinal syndromes were examined for the presence of rotavirus, norovirus, astrovirus, adenovirus, rhinovirus, enterovirus, parechovirus, bocavirus, coronavirus, sapovirus, cosavirus, and aichi virus using polymerase chain reaction assays. Gastrointestinal viral agents were detected in 246 (36%) patients of the 689 analyzed. Adenovirus and norovirus were the most common viruses in this cohort, while aichi virus was the only gastrointestinal agent not detected. Surprisingly, rhinovirus was one of the most frequently detected viruses. However, a potential association with gastroenteritis remains to be confirmed.
AB - Gastrointestinal viral syndromes are a common cause of morbidity and mortality in humans worldwide. Etiological agents include a large number of viruses encompassing several orders, families, and genera. During the period April 2011 to April 2012, 689 stool samples from as many patients hospitalized at the Fondazione IRCCS Policlinico San Matteo of Pavia exhibiting gastrointestinal syndromes were examined for the presence of rotavirus, norovirus, astrovirus, adenovirus, rhinovirus, enterovirus, parechovirus, bocavirus, coronavirus, sapovirus, cosavirus, and aichi virus using polymerase chain reaction assays. Gastrointestinal viral agents were detected in 246 (36%) patients of the 689 analyzed. Adenovirus and norovirus were the most common viruses in this cohort, while aichi virus was the only gastrointestinal agent not detected. Surprisingly, rhinovirus was one of the most frequently detected viruses. However, a potential association with gastroenteritis remains to be confirmed.
KW - Gastroenteritis
KW - Gastrointestinal viruses
KW - Real-time RT-PCR
KW - Stool samples
UR - http://www.scopus.com/inward/record.url?scp=84885388028&partnerID=8YFLogxK
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U2 - 10.1016/j.diagmicrobio.2013.07.020
DO - 10.1016/j.diagmicrobio.2013.07.020
M3 - Article
C2 - 24035383
AN - SCOPUS:84885388028
SN - 0732-8893
VL - 77
SP - 231
EP - 235
JO - Diagnostic Microbiology and Infectious Disease
JF - Diagnostic Microbiology and Infectious Disease
IS - 3
ER -