Natural Killer (NK) cells are lymphoid cells that participate in innate immunity and in early defense against infections and tumors. NK cells express cell surface activating and inhibitory receptors that allow them to recognize and kill infected or tumor cells and rapidly produce cytokines and chemokines. Increasing evidence asserts an important immunomodulatory role of NK cells. We will discuss different mechanisms used by NK cells to regulate T cell-mediated immune responses.
|Title of host publication||Natural Killer Cells: At the Forefront of Modern Immunology|
|Publisher||Springer Berlin Heidelberg|
|Number of pages||13|
|Publication status||Published - 2010|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)