Modificazioni dell'eccitabilità corticale in pazienti con epilessia mioclonica progressiva

Translated title of the contribution: Modification of cortical excitability in progressive myoclonus epilepsy

L. Canafoglia, S. Franceschetti, C. Ciano, V. Scaioli, S. Binelli, F. Panzica, G. Avanzini

Research output: Contribution to journalArticlepeer-review


We analysed cortical excitability in 17 patients with progressive myoclonus epilepsy by means of several neurophysiological ťechniques. The applied tests, including SSEP, long-loop reflex and transcranial magnetic stimulation were able to detect in 16 cases signs of abnormal excitability involving somatosensory or motor cortex. In four cases, topiramate (TPM) induced a significant clinical improvement that corresponded to normalisation of neurophysiological findings.

Translated title of the contributionModification of cortical excitability in progressive myoclonus epilepsy
Original languageItalian
Pages (from-to)125-126
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number113-114
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Clinical Neurology


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