TY - JOUR
T1 - Minimal prevalence of HPV vaccination and common occurrence of high-risk HPV types in pregnant women with HIV
T2 - data from a national study in Italy
AU - on behalf of The Italian Group on Surveillance of Antiretroviral Treatment in Pregnancy
AU - Floridia, Marco
AU - Masuelli, Giulia
AU - Tassis, Beatrice
AU - Savasi, Valeria M.
AU - Sansone, Matilde
AU - Spinillo, Arsenio
AU - Franceschetti, Laura
AU - Guaraldi, Giovanni
AU - Pinnetti, Carmela
AU - Dalzero, Serena
AU - Meloni, Alessandra
AU - Vimercati, Antonella
AU - Simonazzi, Giuliana
AU - Tamburrini, Enrica
AU - Ravizza, Marina
N1 - Funding Information:
This work (currently not funded) was supported in the past by public research grants (ref.: H85E08000200005) from the Italian Medicines Agency (AIFA).
Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2022
Y1 - 2022
N2 - Among 733 pregnant women with HIV followed between 2013 and 2021, only 8 (1.1%) had prior HPV vaccination. One had low-grade squamous intraepithelial lesions [LSIL], and none had HPV type information. Among the 725 non-vaccinated women, 578 (79.7%) had information on cervical cytology. Rate of cytologic abnormalities in this group was 20.6% (0.2% atypical glandular cells of undetermined significance [AGC], 1.7% atypical squamous cells of undetermined significance [ASC-US], 11.1% LSIL, and 7.6% high-grade squamous intraepithelial lesions [HSIL]). Among 56 women with HPV type information, 75.0% carried high risk types, with similar occurrence in women with and without cytologic abnormalities, 30.4% had multiple high-risk types, and 75.9% carried at least one of the types included in the currently recommended 9-valent vaccine.
AB - Among 733 pregnant women with HIV followed between 2013 and 2021, only 8 (1.1%) had prior HPV vaccination. One had low-grade squamous intraepithelial lesions [LSIL], and none had HPV type information. Among the 725 non-vaccinated women, 578 (79.7%) had information on cervical cytology. Rate of cytologic abnormalities in this group was 20.6% (0.2% atypical glandular cells of undetermined significance [AGC], 1.7% atypical squamous cells of undetermined significance [ASC-US], 11.1% LSIL, and 7.6% high-grade squamous intraepithelial lesions [HSIL]). Among 56 women with HPV type information, 75.0% carried high risk types, with similar occurrence in women with and without cytologic abnormalities, 30.4% had multiple high-risk types, and 75.9% carried at least one of the types included in the currently recommended 9-valent vaccine.
KW - Cervical cytology
KW - Cervical HPV
KW - HIV
KW - HPV types
KW - HPV vaccination
KW - Women
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U2 - 10.1007/s10096-021-04393-1
DO - 10.1007/s10096-021-04393-1
M3 - Article
AN - SCOPUS:85122783743
SN - 0934-9723
JO - European Journal of Clinical Microbiology and Infectious Diseases
JF - European Journal of Clinical Microbiology and Infectious Diseases
ER -