Migrainous stroke and the antiphospholipid antibodies

M. Silvestrini, M. Matteis, E. Troisi, L. M. Cupini, G. Zaccari, G. Bernardi

Research output: Contribution to journalArticlepeer-review


The pathogenesis of migrainous stroke is controversial. The possibility that a number of migraine-related strokes is associated with the presence of antiphospholipid antibodies, a condition predisposing to coagulopathy, has been suggested. We investigated the prevalence of lupus anticoagulant and anticardiolipin antibodies in patients with migrainous stroke. In 6 out of 16 patients with migrainous cerebral infarction, the presence of antiphospholipids antibodies was detected. In such patients, the presence of other risk factors for stroke was significantly lower (χ2 = 5.6, p = 0.01) with respect to patients with negative results for antiphospholipid antibodies. These results suggest that antiphospholipid antibodies associated with migraine may be an important marker for ischemic stroke.

Original languageEnglish
Pages (from-to)316-319
Number of pages4
JournalEuropean Neurology
Issue number6
Publication statusPublished - 1994


  • Anticardiolipin antibodies
  • Lupus anticoagulant
  • Migranous stroke

ASJC Scopus subject areas

  • Clinical Neurology


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