MicroRNAs and the control of heart pathophysiology

D. Catalucci; M. V G Latronico; G. Condorelli

doi:10.1007/978-3-540-78709-9_4

MicroRNAs and the control of heart pathophysiology

D. Catalucci, M. V G Latronico, G. Condorelli

Istituto Clinico Humanitas

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

MicroRNAs (miRNAs) are small, endogenous, non-coding RNAs that control gene expression at a posttranscriptional level. They are one of the most abundant class of gene regulatory molecules in multicellular organisms, and are being implicated in an increasing number of biological processes. Many miRNAs are expressed in a tissue-specific manner during development and take part in the regulation of cell-lineage decisions and morphogenesis. Moreover, much work is now highlighting their importance for malformations and disease. This chapter presents knowledge on miRNA biology, and then describes the recent findings regarding aspects of cardiovascular pathophysiology.

Original language	English
Title of host publication	RNA Technologies in Cardiovascular Medicine and Research
Publisher	Springer-Verlag Berlin Heidelberg
Pages	53-68
Number of pages	16
ISBN (Print)	9783540787099, 9783540787082
DOIs	https://doi.org/10.1007/978-3-540-78709-9_4
Publication status	Published - 2008

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)

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10.1007/978-3-540-78709-9_4

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MicroRNAs and the control of heart pathophysiology

Abstract

ASJC Scopus subject areas

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