MicroRNAs and the control of heart pathophysiology

Research output: Chapter in Book/Report/Conference proceedingChapter


MicroRNAs (miRNAs) are small, endogenous, non-coding RNAs that control gene expression at a posttranscriptional level. They are one of the most abundant class of gene regulatory molecules in multicellular organisms, and are being implicated in an increasing number of biological processes. Many miRNAs are expressed in a tissue-specific manner during development and take part in the regulation of cell-lineage decisions and morphogenesis. Moreover, much work is now highlighting their importance for malformations and disease. This chapter presents knowledge on miRNA biology, and then describes the recent findings regarding aspects of cardiovascular pathophysiology.

Original languageEnglish
Title of host publicationRNA Technologies in Cardiovascular Medicine and Research
PublisherSpringer-Verlag Berlin Heidelberg
Number of pages16
ISBN (Print)9783540787099, 9783540787082
Publication statusPublished - 2008

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)


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