Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) was identified in clinical isolates only a few years after the introduction of this drug in clinical practice. This resistance trait has become common and spread worldwide due to the diffusion of epidemic clones, and MRSA has become one of the most frequently isolated nosocomial pathogens. Recently, methicillin-resistant isolates either from livestock or that were community-acquired have gained importance in clinical microbiology. The incidence of MRSA currently varies from country to country and, in the same country, from hospital to hospital. In this chapter, the mechanism of methicillin resistance is described, with particular emphasis on the structure of the SCC. mec cassette and details regarding differentiation of these isolates from a molecular point of view.
| Original language | English |
|---|---|
| Title of host publication | Pet-to-Man Travelling Staphylococci |
| Subtitle of host publication | A World in Progress |
| Publisher | Elsevier Inc. |
| Pages | 225-235 |
| Number of pages | 11 |
| ISBN (Electronic) | 9780128135488 |
| ISBN (Print) | 9780128135471 |
| DOIs | |
| Publication status | Published - Mar 16 2018 |
| Externally published | Yes |
Keywords
- MecA gene
- MecC gene
- Methicillin resistance
- Molecular detection of resistance traits
- SCCmec cassette
ASJC Scopus subject areas
- Immunology and Microbiology(all)