TY - JOUR
T1 - Melanocyte colonization and pigmentation of breast carcinoma
T2 - Description of two pathological cases and review of literature
AU - Santoro, Angela
AU - Angelico, Giuseppe
AU - Fiorentino, Vincenzo
AU - Zhang, Qianqian
AU - Spadola, Saveria
AU - Carlino, Angela
AU - Sanchez, Alejandro Martin
AU - Franceschini, Gianluca
AU - Zannoni, Gian Franco
AU - Mulè, Antonino
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/4
Y1 - 2021/4
N2 - Colonization of breast carcinoma by non-neoplastic melanocytes of epidermal origin was first described by Azzopardi and Eusebi in 1977. We herein report two cases on the exceptional clinical and pathological features of this phenomenon in a 66-year-old and a 51-year-old patients. The pathogenesis is not fully understood, but a disrupted basement membrane and the role of tumoral growth factors are considered essential.
AB - Colonization of breast carcinoma by non-neoplastic melanocytes of epidermal origin was first described by Azzopardi and Eusebi in 1977. We herein report two cases on the exceptional clinical and pathological features of this phenomenon in a 66-year-old and a 51-year-old patients. The pathogenesis is not fully understood, but a disrupted basement membrane and the role of tumoral growth factors are considered essential.
KW - Breast carcinoma
KW - Breast melanosis
KW - Melanocyte colonization
KW - Melanoma
KW - Pigmentation
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UR - http://www.scopus.com/inward/citedby.url?scp=85109103668&partnerID=8YFLogxK
U2 - 10.3390/diagnostics11040709
DO - 10.3390/diagnostics11040709
M3 - Article
AN - SCOPUS:85109103668
SN - 2075-4418
VL - 11
JO - Diagnostics
JF - Diagnostics
IS - 4
M1 - 709
ER -