TY - JOUR
T1 - Lung ultrasound features of children with complicated and noncomplicated community acquired pneumonia
T2 - A prospective study
AU - Musolino, Anna Maria
AU - Tomà, Paolo
AU - Supino, Maria Chiara
AU - Scialanga, Barbara
AU - Mesturino, Alessia
AU - Scateni, Simona
AU - Battaglia, Massimo
AU - Pirozzi, Nicola
AU - Bock, Caterina
AU - Buonsenso, Danilo
N1 - © 2019 Wiley Periodicals, Inc.
PY - 2019/9
Y1 - 2019/9
N2 - OBJECTIVE: The purpose of this study was to describe lung ultrasound (LUS) findings at baseline and 48 hours after the beginning of treatment and evaluate how they correlate with outcome DESIGN: We prospectively analyzed patients from 1 month to 17 years of age with community acquired pneumonia (CAP) evaluated at a tertiary level pediatric hospital. At baseline and 48 hours after the beginning of treatment, history, clinical examination, laboratory testing, chest X-ray, and LUS were performed.RESULTS: One hundred one children were enrolled in the study (13 with complicated CAP). At baseline those who developed complications presented a larger size of the subpleural pulmonary parenchymal lesions (P = .001) often associated with a complex pleural effusion (63.6%, P = .013). Those with an uncomplicated CAP presented an air, arboriform, superficial and dynamic bronchogram, as opposed to complicated CAP which had an air and liquid bronchogram, deep, fixed (P = .001). At the 48-hour control in the noncomplicated CAP group, bronchogram was more frequently superficial and dynamic (P = .050). Pleural effusion disappeared in half cases (P = .050). In all patients, neutrophilic leucocytosis with increased C-reactive protein was detected and decreased at control (P = .001). The linear regression analyses showed the switch from a deep to a superficial bronchogram as the only explanatory variable (r = 0.97, R2 = 0.94, P = .001, t = 10.73).CONCLUSIONS: Our study describe early LUS features of CAP that might be able to predict the development of complicated CAP.
AB - OBJECTIVE: The purpose of this study was to describe lung ultrasound (LUS) findings at baseline and 48 hours after the beginning of treatment and evaluate how they correlate with outcome DESIGN: We prospectively analyzed patients from 1 month to 17 years of age with community acquired pneumonia (CAP) evaluated at a tertiary level pediatric hospital. At baseline and 48 hours after the beginning of treatment, history, clinical examination, laboratory testing, chest X-ray, and LUS were performed.RESULTS: One hundred one children were enrolled in the study (13 with complicated CAP). At baseline those who developed complications presented a larger size of the subpleural pulmonary parenchymal lesions (P = .001) often associated with a complex pleural effusion (63.6%, P = .013). Those with an uncomplicated CAP presented an air, arboriform, superficial and dynamic bronchogram, as opposed to complicated CAP which had an air and liquid bronchogram, deep, fixed (P = .001). At the 48-hour control in the noncomplicated CAP group, bronchogram was more frequently superficial and dynamic (P = .050). Pleural effusion disappeared in half cases (P = .050). In all patients, neutrophilic leucocytosis with increased C-reactive protein was detected and decreased at control (P = .001). The linear regression analyses showed the switch from a deep to a superficial bronchogram as the only explanatory variable (r = 0.97, R2 = 0.94, P = .001, t = 10.73).CONCLUSIONS: Our study describe early LUS features of CAP that might be able to predict the development of complicated CAP.
U2 - 10.1002/ppul.24426
DO - 10.1002/ppul.24426
M3 - Article
C2 - 31264383
SN - 8755-6863
VL - 54
SP - 1479
EP - 1486
JO - Pediatric Pulmonology
JF - Pediatric Pulmonology
IS - 9
ER -