TY - JOUR
T1 - Low-power diode laser stimulation of surgical osteochondral defects
T2 - Results after 24 weeks
AU - Guzzardella, G. A.
AU - Tigani, D.
AU - Torricelli, P.
AU - Fini, M.
AU - Martini, L.
AU - Morrone, G.
AU - Giardino, R.
PY - 2001
Y1 - 2001
N2 - The purpose of this study was to evaluate osteochondral lesions of the knee, treated intraoperatively with low-power laser stimulation, and assess results at 24 weeks. Surgery was performed under general anesthesia on six rabbits; a bilateral osteochondral lesion was created in the femoral medial condyles with a drill. All of the left lesions underwent immediate stimulation using the diode Ga-Al-As laser (780nm), whereas the right knees were left untreated as control group. After 24 weeks, the explants from the femoral condyles, either treated employing laser energy or left untreated, were examined histomorphometrically. Results obtained on the lased condyles showed good cell morphology and a regular aspect of the repaired osteocartilaginous tissue.
AB - The purpose of this study was to evaluate osteochondral lesions of the knee, treated intraoperatively with low-power laser stimulation, and assess results at 24 weeks. Surgery was performed under general anesthesia on six rabbits; a bilateral osteochondral lesion was created in the femoral medial condyles with a drill. All of the left lesions underwent immediate stimulation using the diode Ga-Al-As laser (780nm), whereas the right knees were left untreated as control group. After 24 weeks, the explants from the femoral condyles, either treated employing laser energy or left untreated, were examined histomorphometrically. Results obtained on the lased condyles showed good cell morphology and a regular aspect of the repaired osteocartilaginous tissue.
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U2 - 10.1081/BIO-100103047
DO - 10.1081/BIO-100103047
M3 - Article
C2 - 11358039
AN - SCOPUS:0035019945
SN - 1073-1199
VL - 29
SP - 235
EP - 244
JO - Artificial Cells, Blood Substitutes, and Immobilization Biotechnology
JF - Artificial Cells, Blood Substitutes, and Immobilization Biotechnology
IS - 3
ER -