Low-grade myofibroblastic sarcoma of the larynx

Renato Covello, Stefano Licci, Barbara Pichi, Giuseppe Spriano, Antonello Vidiri, Luca Morelli, Andrew E. Rosenberg

Research output: Contribution to journalArticlepeer-review


Low-grade myofibroblastic sarcoma is an uncommon sarcoma with myofibroblastic differentiation. It occurs in a wide variety of sites and has a predilection for the head and neck region. Biologically, low-grade myofibroblastic sarcoma has a propensity for local recurrence and is associated with a low risk of metastatic spread. Histologically, it can mimic a variety of different types of benign and malignant processes and often requires immunohistochemical analysis for its accurate identification. This report describes a case and discusses the differential diagnosis of a low-grade myofibroblastic sarcoma that arose in the larynx of a 69-year-old woman with a history of metastatic skin melanoma. To the best of the authors' knowledge this is the first description in the English literature of low-grade myofibroblastic sarcoma originating in the larynx.

Original languageEnglish
Pages (from-to)822-826
Number of pages5
JournalInternational Journal of Surgical Pathology
Issue number6
Publication statusPublished - Dec 2011


  • head and neck
  • larynx
  • low-grade myofibroblastic sarcoma

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine
  • Surgery


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