Abstract
Aim. The aim of this study was to evaluate the analgesic effects of remifentanyl® on mechanically ventilated newborns. Methods. Eighteen newborns, mechanically ventilated, were submitted to continuous infusion of R. A pain scale was used to evaluate comfort during mechanical ventilation. Data were collected at T0, T1, Tn, T ext, T post-ext; statistical analysis was performed by Student's t test and Pearson coefficient. Results. Mean R infusion time was 66.94±22.24 h, with mean dose of R 0.146±0.038 γ/kg/min. Mean time to reach comfort was 20±13.11 h with a mean infusion of R equal to 0.173±0.146 γ/kg/min; R was 0.18±0.039 γ/kg/min on pressure controlled ventilation and R was 0.09± 0.045 γ/kg/min on assisted ventilation. Statistically significant was considered the decrease in HR as well as the increase of SpO2 at T0 vs 30 min after infusion. Conclusion. No adverse effects were observed during and after infusion.
| Translated title of the contribution | Low dose remifentanyl infusion for analgesia and sedation in ventilated newborns |
|---|---|
| Original language | Italian |
| Pages (from-to) | 753-761 |
| Number of pages | 9 |
| Journal | Minerva Anestesiologica |
| Volume | 70 |
| Issue number | 11 |
| Publication status | Published - Nov 2004 |
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine