Long-term follow up of subthalamic nucleus stimulation in Parkinson's disease

L. M A Romito; M. Scerrati; M. F. Contarino; A. R. Bentivoglio; P. Tonali; A. Albanese

Long-term follow up of subthalamic nucleus stimulation in Parkinson's disease

L. M A Romito, M. Scerrati, M. F. Contarino, A. R. Bentivoglio, P. Tonali, A. Albanese

Fondazione IRCCS Istituto Neurologico "C. Besta"

Research output: Contribution to journal › Article › peer-review

Abstract

Twenty-two patients with PD received bilateral implants for high frequency stimulation of the subthalamic nucleus. The patients were treated for more than 1 year (up to 36 months). At the last visit, the Unified Parkinson Disease Rating Scale (UPDRS) motor score without medication improved by 50.2% (p <0.001) and the UPDRS activities of daily living score improved by 68.4% (p <0.001). The most common long-lasting adverse events were hypophonia and dysarthria; transient events were increased sexuality and mania. The surgical procedure induced transient intraoperative psychosis in seven patients.

Original language	English
Pages (from-to)	1546-1550
Number of pages	5
Journal	Neurology
Volume	58
Issue number	10
Publication status	Published - May 28 2002

ASJC Scopus subject areas

Neuroscience(all)

Cite this

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abstract = "Twenty-two patients with PD received bilateral implants for high frequency stimulation of the subthalamic nucleus. The patients were treated for more than 1 year (up to 36 months). At the last visit, the Unified Parkinson Disease Rating Scale (UPDRS) motor score without medication improved by 50.2% (p <0.001) and the UPDRS activities of daily living score improved by 68.4% (p <0.001). The most common long-lasting adverse events were hypophonia and dysarthria; transient events were increased sexuality and mania. The surgical procedure induced transient intraoperative psychosis in seven patients.",

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AU - Romito, L. M A

AU - Scerrati, M.

AU - Contarino, M. F.

AU - Bentivoglio, A. R.

AU - Tonali, P.

AU - Albanese, A.

PY - 2002/5/28

Y1 - 2002/5/28

N2 - Twenty-two patients with PD received bilateral implants for high frequency stimulation of the subthalamic nucleus. The patients were treated for more than 1 year (up to 36 months). At the last visit, the Unified Parkinson Disease Rating Scale (UPDRS) motor score without medication improved by 50.2% (p <0.001) and the UPDRS activities of daily living score improved by 68.4% (p <0.001). The most common long-lasting adverse events were hypophonia and dysarthria; transient events were increased sexuality and mania. The surgical procedure induced transient intraoperative psychosis in seven patients.

AB - Twenty-two patients with PD received bilateral implants for high frequency stimulation of the subthalamic nucleus. The patients were treated for more than 1 year (up to 36 months). At the last visit, the Unified Parkinson Disease Rating Scale (UPDRS) motor score without medication improved by 50.2% (p <0.001) and the UPDRS activities of daily living score improved by 68.4% (p <0.001). The most common long-lasting adverse events were hypophonia and dysarthria; transient events were increased sexuality and mania. The surgical procedure induced transient intraoperative psychosis in seven patients.

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Long-term follow up of subthalamic nucleus stimulation in Parkinson's disease

Abstract

ASJC Scopus subject areas

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