Long-term follow up of subthalamic nucleus stimulation in Parkinson's disease

L. M A Romito, M. Scerrati, M. F. Contarino, A. R. Bentivoglio, P. Tonali, A. Albanese

Research output: Contribution to journalArticlepeer-review


Twenty-two patients with PD received bilateral implants for high frequency stimulation of the subthalamic nucleus. The patients were treated for more than 1 year (up to 36 months). At the last visit, the Unified Parkinson Disease Rating Scale (UPDRS) motor score without medication improved by 50.2% (p <0.001) and the UPDRS activities of daily living score improved by 68.4% (p <0.001). The most common long-lasting adverse events were hypophonia and dysarthria; transient events were increased sexuality and mania. The surgical procedure induced transient intraoperative psychosis in seven patients.

Original languageEnglish
Pages (from-to)1546-1550
Number of pages5
Issue number10
Publication statusPublished - May 28 2002

ASJC Scopus subject areas

  • Neuroscience(all)


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