Long-term follow-up of patients with first-time chest pain having 64-slice computed tomography

Fabiola B. Sozzi, Filippo Civaia, Philippe Rossi, Jean Francois Robillon, Stephane Rusek, Frederic Berthier, Francois Bourlon, Laura Iacuzio, Gilles Dreyfus, Vincent Dor

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A paucity of data on outcome of coronary multislice computed tomography (CT) is available. The aim of this study was to assess the long-term follow-up of 64-slice CT in a homogenous patient group. In total 222 patients (136 men, 61%, 59 ± 11 years of age) with chest pain at intermediate risk of coronary artery disease (CAD) and no previous CAD underwent 64-slice CT. Coronary lesions were considered significant or not based on a threshold of 50% luminal narrowing. Plaques were classified as calcified, noncalcified, and mixed based on type. End point during follow-up was major adverse cardiac events (nonfatal myocardial infarction, unstable angina requiring hospitalization, myocardial revascularization). Coronary plaques were detected in 162 patients (73%). Coronary artery stenosis was significant in 62 patients. Normal arteries were found in 59 patients (27%). During a mean follow-up of 5 ± 0.5 years, 30 cardiac events occurred. Annualized event rates were 0% in patients with normal coronary arteries, 1.2% in patients with nonsignificant stenosis, and 4.2% in patients with significant stenosis (p

Original languageEnglish
Pages (from-to)516-521
Number of pages6
JournalThe American Journal of Cardiology
Issue number4
Publication statusPublished - Feb 15 2011

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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