Long-term disease-free acute myeloblastic leukemia with inv(16) is associated with PCR undetectable CBFβ/MYH11 transcript

Giovanni Martinelli; Emanuela Ottaviani; Nicoletta Testoni; Vittorio Montefusco; Silvia Buonamici; Sante Tura

Long-term disease-free acute myeloblastic leukemia with inv(16) is associated with PCR undetectable CBFβ/MYH11 transcript

Giovanni Martinelli, Emanuela Ottaviani, Nicoletta Testoni, Vittorio Montefusco, Silvia Buonamici, Sante Tura

Fondazione IRCCS Istituto Nazionale dei Tumori

Research output: Contribution to journal › Article › peer-review

Abstract

This study investigates the benefits of minimal residual disease in a subset of AML patients with inv(16) by means of non-quantitative detection of CBFβ/MYH11 fusion transcript. We found that CBFβ/MYH11 RT-PCR negativity is associated with cure of disease.

Original language	English
Pages (from-to)	552-554
Number of pages	3
Journal	Haematologica
Volume	85
Issue number	5
Publication status	Published - May 2000

ASJC Scopus subject areas

Hematology

Cite this

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title = "Long-term disease-free acute myeloblastic leukemia with inv(16) is associated with PCR undetectable CBFβ/MYH11 transcript",

abstract = "This study investigates the benefits of minimal residual disease in a subset of AML patients with inv(16) by means of non-quantitative detection of CBFβ/MYH11 fusion transcript. We found that CBFβ/MYH11 RT-PCR negativity is associated with cure of disease.",

author = "Giovanni Martinelli and Emanuela Ottaviani and Nicoletta Testoni and Vittorio Montefusco and Silvia Buonamici and Sante Tura",

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AU - Martinelli, Giovanni

AU - Ottaviani, Emanuela

AU - Testoni, Nicoletta

AU - Montefusco, Vittorio

AU - Buonamici, Silvia

AU - Tura, Sante

PY - 2000/5

Y1 - 2000/5

N2 - This study investigates the benefits of minimal residual disease in a subset of AML patients with inv(16) by means of non-quantitative detection of CBFβ/MYH11 fusion transcript. We found that CBFβ/MYH11 RT-PCR negativity is associated with cure of disease.

AB - This study investigates the benefits of minimal residual disease in a subset of AML patients with inv(16) by means of non-quantitative detection of CBFβ/MYH11 fusion transcript. We found that CBFβ/MYH11 RT-PCR negativity is associated with cure of disease.

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IS - 5

ER -

Long-term disease-free acute myeloblastic leukemia with inv(16) is associated with PCR undetectable CBFβ/MYH11 transcript

Abstract

ASJC Scopus subject areas

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