Long term complete remission of severe nephrotic syndrome secondary to diffuse global (IV-G) lupus nephritis following autologous, haematopoietic peripheral stem (CD34+) cell transplantation

A. M. Marmont; F. Gualandi; M. T. Van Lint; C. Guastoni; A. Bacigalupo

doi:10.1191/0961203306lu2241cr

Long term complete remission of severe nephrotic syndrome secondary to diffuse global (IV-G) lupus nephritis following autologous, haematopoietic peripheral stem (CD34+) cell transplantation

A. M. Marmont, F. Gualandi, M. T. Van Lint, C. Guastoni, A. Bacigalupo

A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)

Research output: Contribution to journal › Article › peer-review

Abstract

Autologous haematopoietic stem cell transplantation has become an accepted powerful therapeutic procedure for patients with severe, intractable SLE. Here we describe a 26-year old patient with stage IV-G diffuse global proliferative lupus nephritis and refractory nephrotic syndrome who responded to autologous peripheral stem cell transplantation (ASCT) after two mobilization procedures. Five years later the patient is in complete clinical and immunologie remission. The indications for ASCT and its mechanism of action are briefly discussed.

Original language	English
Pages (from-to)	44-46
Number of pages	3
Journal	Lupus
Volume	15
Issue number	1
DOIs	https://doi.org/10.1191/0961203306lu2241cr
Publication status	Published - 2006

Keywords

Autologous stem cell transplantation
Lupus nephritis
Nephrotic syndrome

ASJC Scopus subject areas

Rheumatology
Immunology

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10.1191/0961203306lu2241cr

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abstract = "Autologous haematopoietic stem cell transplantation has become an accepted powerful therapeutic procedure for patients with severe, intractable SLE. Here we describe a 26-year old patient with stage IV-G diffuse global proliferative lupus nephritis and refractory nephrotic syndrome who responded to autologous peripheral stem cell transplantation (ASCT) after two mobilization procedures. Five years later the patient is in complete clinical and immunologie remission. The indications for ASCT and its mechanism of action are briefly discussed.",

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AU - Marmont, A. M.

AU - Gualandi, F.

AU - Van Lint, M. T.

AU - Guastoni, C.

AU - Bacigalupo, A.

PY - 2006

Y1 - 2006

N2 - Autologous haematopoietic stem cell transplantation has become an accepted powerful therapeutic procedure for patients with severe, intractable SLE. Here we describe a 26-year old patient with stage IV-G diffuse global proliferative lupus nephritis and refractory nephrotic syndrome who responded to autologous peripheral stem cell transplantation (ASCT) after two mobilization procedures. Five years later the patient is in complete clinical and immunologie remission. The indications for ASCT and its mechanism of action are briefly discussed.

AB - Autologous haematopoietic stem cell transplantation has become an accepted powerful therapeutic procedure for patients with severe, intractable SLE. Here we describe a 26-year old patient with stage IV-G diffuse global proliferative lupus nephritis and refractory nephrotic syndrome who responded to autologous peripheral stem cell transplantation (ASCT) after two mobilization procedures. Five years later the patient is in complete clinical and immunologie remission. The indications for ASCT and its mechanism of action are briefly discussed.

KW - Autologous stem cell transplantation

KW - Lupus nephritis

KW - Nephrotic syndrome

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Long term complete remission of severe nephrotic syndrome secondary to diffuse global (IV-G) lupus nephritis following autologous, haematopoietic peripheral stem (CD34+) cell transplantation

Abstract

Keywords

ASJC Scopus subject areas

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