Localized peeling skin syndrome: Case report with ultrastructural study

A. Brusasco, S. Veraldi, G. Tadini, R. Caputo

Research output: Contribution to journalArticlepeer-review


We report a young woman in whom the history, clinical features, histopathological and ultrastructural findings led to a diagnosis of peeling skin syndrome (PSS). PSS is a rare and not well classified genodermatosis, mainly characterized by the spontaneous separation of the stratum corneum from the stratum granulosum. The unusual feature in our patient was the strict localization to the palm. PSS has been described as a more generalized disease frequently sparing palms and soles. We propose the diagnosis label of 'localized PSS' for this previously undescribed variant of a rare keratinization defect.

Original languageEnglish
Pages (from-to)492-495
Number of pages4
JournalBritish Journal of Dermatology
Issue number3
Publication statusPublished - 1998

ASJC Scopus subject areas

  • Dermatology


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