Localization of Th-cell subsets in inflammation: Differential thresholds for extravasation of Th1 and Th2 cells

Daniele D'Ambrosio; Andrea Iellem; Lucia Colantonio; Barbara Clissi; Ruggero Pardi; Francesco Sinigaglia

doi:10.1016/S0167-5699(00)01590-5

Localization of Th-cell subsets in inflammation: Differential thresholds for extravasation of Th1 and Th2 cells

Daniele D'Ambrosio, Andrea Iellem, Lucia Colantonio, Barbara Clissi, Ruggero Pardi, Francesco Sinigaglia

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

The recruitment of T helper 1 (Th1) and Th2 cells into peripheral tissues is essential for inflammation and the host response to infections. Here, Daniele D'Ambrosio and colleagues review the traffic signals that enable the distinct positioning of Th1 and Th2 cells and argue that differential thresholds for extravasation constitute a critical aspect of their selective localization to inflamed tissues.

Original language	English
Pages (from-to)	183-186
Number of pages	4
Journal	Immunology Today
Volume	21
Issue number	4
DOIs	https://doi.org/10.1016/S0167-5699(00)01590-5
Publication status	Published - Apr 1 2000

ASJC Scopus subject areas

Immunology

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10.1016/S0167-5699(00)01590-5

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abstract = "The recruitment of T helper 1 (Th1) and Th2 cells into peripheral tissues is essential for inflammation and the host response to infections. Here, Daniele D'Ambrosio and colleagues review the traffic signals that enable the distinct positioning of Th1 and Th2 cells and argue that differential thresholds for extravasation constitute a critical aspect of their selective localization to inflamed tissues.",

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AU - Iellem, Andrea

AU - Colantonio, Lucia

AU - Clissi, Barbara

AU - Pardi, Ruggero

AU - Sinigaglia, Francesco

PY - 2000/4/1

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AB - The recruitment of T helper 1 (Th1) and Th2 cells into peripheral tissues is essential for inflammation and the host response to infections. Here, Daniele D'Ambrosio and colleagues review the traffic signals that enable the distinct positioning of Th1 and Th2 cells and argue that differential thresholds for extravasation constitute a critical aspect of their selective localization to inflamed tissues.

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Localization of Th-cell subsets in inflammation: Differential thresholds for extravasation of Th1 and Th2 cells

Abstract

ASJC Scopus subject areas

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