Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome:: A case report

V. Pingue; M. Gentili; A. Losurdo; E. Clementi; A. Nardone

doi:10.3389/fnins.2020.00070

Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome: A case report

V. Pingue, M. Gentili, A. Losurdo, E. Clementi, A. Nardone

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Abstract

Severe spasticity is a frequent and disabling complication in patients presenting disorders of consciousness (DOC) that hinders their rehabilitative process, and is strongly correlated with pain reducing patients’ quality of life. In these patients, abnormal postures may occur as an expression of severe brain damage. Here we present the case of a 52-year-old man in decorticate rigidity following a hypoxic–ischemic encephalopathy due to myocardial infarction who showed improvement of spasticity of upper limbs following intake of levetiracetam combined with the conventional neurorehabilitation program. © Copyright © 2020 Pingue, Gentili, Losurdo, Clementi and Nardone.

Original language	English
Article number	70
Journal	Frontiers in Neuroscience
Volume	14
DOIs	https://doi.org/10.3389/fnins.2020.00070
Publication status	Published - 2020

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title = "Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome:: A case report",

abstract = "Severe spasticity is a frequent and disabling complication in patients presenting disorders of consciousness (DOC) that hinders their rehabilitative process, and is strongly correlated with pain reducing patients{\textquoteright} quality of life. In these patients, abnormal postures may occur as an expression of severe brain damage. Here we present the case of a 52-year-old man in decorticate rigidity following a hypoxic–ischemic encephalopathy due to myocardial infarction who showed improvement of spasticity of upper limbs following intake of levetiracetam combined with the conventional neurorehabilitation program. {\textcopyright} Copyright {\textcopyright} 2020 Pingue, Gentili, Losurdo, Clementi and Nardone.",

author = "V. Pingue and M. Gentili and A. Losurdo and E. Clementi and A. Nardone",

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T1 - Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome:

T2 - A case report

AU - Pingue, V.

AU - Gentili, M.

AU - Losurdo, A.

AU - Clementi, E.

AU - Nardone, A.

N1 - Export Date: 2 February 2021

PY - 2020

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AB - Severe spasticity is a frequent and disabling complication in patients presenting disorders of consciousness (DOC) that hinders their rehabilitative process, and is strongly correlated with pain reducing patients’ quality of life. In these patients, abnormal postures may occur as an expression of severe brain damage. Here we present the case of a 52-year-old man in decorticate rigidity following a hypoxic–ischemic encephalopathy due to myocardial infarction who showed improvement of spasticity of upper limbs following intake of levetiracetam combined with the conventional neurorehabilitation program. © Copyright © 2020 Pingue, Gentili, Losurdo, Clementi and Nardone.

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VL - 14

JO - Frontiers in Neuroscience

JF - Frontiers in Neuroscience

M1 - 70

ER -

Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome: A case report

Abstract

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