TY - JOUR
T1 - Left thalamomegaly in a patient with partial epilepsy
AU - Della Marca, Giacomo
AU - Vollono, Catello
AU - Ferraro, Diana
AU - Mariotti, Paolo
AU - Mazza, Marianna
AU - Ferini-Strambi, Luigi
AU - Mazza, Salvatore
PY - 2008/3
Y1 - 2008/3
N2 - Temporal lobe epilepsy (TLE) is associated with modification in thalamic structure and function. In particular, thalamic atrophy and hypometabolism can occur, affecting ipsilateral, contralateral thalami or both. We describe a 28-year-old epileptic woman, who presented peculiar neuroimaging findings, with enlargement of the thalamus contralateral to the epileptic focus. The patient was born from dystocic delivery, she presented partial motor seizures in the left side of the body, followed by generalisation, and the EEG showed a right temporal epileptic focus. Serial CT and MRI scan, performed along 11 years, showed a non-evolutive left thalamomegaly. 18-FDG PET showed reduced metabolic activity in the upper right temporal gyrus and in the ipsilateral thalamus. Thalamic asymmetry in our patient could be an occasional finding.
AB - Temporal lobe epilepsy (TLE) is associated with modification in thalamic structure and function. In particular, thalamic atrophy and hypometabolism can occur, affecting ipsilateral, contralateral thalami or both. We describe a 28-year-old epileptic woman, who presented peculiar neuroimaging findings, with enlargement of the thalamus contralateral to the epileptic focus. The patient was born from dystocic delivery, she presented partial motor seizures in the left side of the body, followed by generalisation, and the EEG showed a right temporal epileptic focus. Serial CT and MRI scan, performed along 11 years, showed a non-evolutive left thalamomegaly. 18-FDG PET showed reduced metabolic activity in the upper right temporal gyrus and in the ipsilateral thalamus. Thalamic asymmetry in our patient could be an occasional finding.
KW - Asymmetry
KW - Epilepsy
KW - Magnetic resonance imaging
KW - Perinatal hypoxia
KW - Positron emission tomography
KW - Thalamus
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U2 - 10.1016/j.clineuro.2007.10.021
DO - 10.1016/j.clineuro.2007.10.021
M3 - Article
C2 - 18096311
AN - SCOPUS:39749163634
SN - 0303-8467
VL - 110
SP - 298
EP - 301
JO - Clinical Neurology and Neurosurgery
JF - Clinical Neurology and Neurosurgery
IS - 3
ER -