Left thalamomegaly in a patient with partial epilepsy

Giacomo Della Marca, Catello Vollono, Diana Ferraro, Paolo Mariotti, Marianna Mazza, Luigi Ferini-Strambi, Salvatore Mazza

Research output: Contribution to journalArticlepeer-review


Temporal lobe epilepsy (TLE) is associated with modification in thalamic structure and function. In particular, thalamic atrophy and hypometabolism can occur, affecting ipsilateral, contralateral thalami or both. We describe a 28-year-old epileptic woman, who presented peculiar neuroimaging findings, with enlargement of the thalamus contralateral to the epileptic focus. The patient was born from dystocic delivery, she presented partial motor seizures in the left side of the body, followed by generalisation, and the EEG showed a right temporal epileptic focus. Serial CT and MRI scan, performed along 11 years, showed a non-evolutive left thalamomegaly. 18-FDG PET showed reduced metabolic activity in the upper right temporal gyrus and in the ipsilateral thalamus. Thalamic asymmetry in our patient could be an occasional finding.

Original languageEnglish
Pages (from-to)298-301
Number of pages4
JournalClinical Neurology and Neurosurgery
Issue number3
Publication statusPublished - Mar 2008


  • Asymmetry
  • Epilepsy
  • Magnetic resonance imaging
  • Perinatal hypoxia
  • Positron emission tomography
  • Thalamus

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Neurology


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