Kaposi's sarcoma of the glans penis in an immunocompetent patient

Alessia Pacifico, Domenico Piccolo, Maria Concetta Fargnoli, Ketty Peris

Research output: Contribution to journalArticlepeer-review


We report a 39-year-old HIV negative man with a solitary reddish-brown papule located on the glans penis, which had developed 6 months previously. Histopathologic examination showed spindle-shaped cells scattered between collagen bundles and intermingled with small, pointed vascular-like spaces. Spindle-shaped cells stained positively for anti-Factor VIII and anti-CD34 antibodies. Human herpes virus-8 DNA was detected in tumor tissue and in peripheral blood mononuclear cells. Based on clinicopathologic and molecular findings, the diagnosis of classic Kaposi's sarcoma was made. Two months after the initial observation, three additional papules developed on the glans penis. Histopathologic examination of one lesion confirmed the diagnosis of classic Kaposi's sarcoma. The remaining lesions were treated with electrodessication and curettage. After a follow-up period of 6 months no evidence of recurrence was observed. We report this case for the unusual localization of Kaposi's Sarcoma in a young, HIV-negative patient.

Original languageEnglish
Pages (from-to)582-583
Number of pages2
JournalEuropean Journal of Dermatology
Issue number6
Publication statusPublished - Nov 2003


  • Classic Kaposi's sarcoma
  • Hemangioproliferative disorders
  • Human herpes virus-8
  • Polymerase chain reaction

ASJC Scopus subject areas

  • Dermatology


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