Juvenile Idiopathic Arthritis

Research output: Chapter in Book/Report/Conference proceedingChapter


Juvenile idiopathic arthritis (JIA) is not a disease, but an exclusion diagnosis that gathers together all forms of arthritis that begin before the age of 16 years, persist for more than 6 weeks, and are of unknown origin. Most of these diseases appear to represent the childhood counterpart of diseases observed in adults. The most notable exceptions are represented by early-onset, ANA-positive arthritis, which is specific to childhood, and by the much higher frequency in children of systemic JIA which is considered the equivalent of adult-onset Still's disease. These two diseases present peculiar clinical and immunological aspects.

Original languageEnglish
Title of host publicationThe Autoimmune Diseases: Fifth Edition
PublisherElsevier Inc.
Number of pages12
ISBN (Print)9780123849298
Publication statusPublished - Dec 2013


  • Early-onset antinuclear antibody-positive arthritis
  • Genetic associations
  • Juvenile idiopathic arthritis (JIA)
  • Macrophage activation syndrome
  • Proinflammatory cytokine
  • Systemic JIA

ASJC Scopus subject areas

  • Immunology and Microbiology(all)


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