Juvenile Idiopathic Arthritis

Clara Malattia; Alberto Martini

doi:10.1016/B978-0-12-384929-8.00037-X

Juvenile Idiopathic Arthritis

Clara Malattia, Alberto Martini

Istituto "Giannina Gaslini"

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Juvenile idiopathic arthritis (JIA) is not a disease, but an exclusion diagnosis that gathers together all forms of arthritis that begin before the age of 16 years, persist for more than 6 weeks, and are of unknown origin. Most of these diseases appear to represent the childhood counterpart of diseases observed in adults. The most notable exceptions are represented by early-onset, ANA-positive arthritis, which is specific to childhood, and by the much higher frequency in children of systemic JIA which is considered the equivalent of adult-onset Still's disease. These two diseases present peculiar clinical and immunological aspects.

Original language	English
Title of host publication	The Autoimmune Diseases: Fifth Edition
Publisher	Elsevier Inc.
Pages	525-536
Number of pages	12
ISBN (Print)	9780123849298
DOIs	https://doi.org/10.1016/B978-0-12-384929-8.00037-X
Publication status	Published - Dec 2013

Keywords

Early-onset antinuclear antibody-positive arthritis
Genetic associations
Juvenile idiopathic arthritis (JIA)
Macrophage activation syndrome
Proinflammatory cytokine
Systemic JIA

ASJC Scopus subject areas

Immunology and Microbiology(all)

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10.1016/B978-0-12-384929-8.00037-X

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abstract = "Juvenile idiopathic arthritis (JIA) is not a disease, but an exclusion diagnosis that gathers together all forms of arthritis that begin before the age of 16 years, persist for more than 6 weeks, and are of unknown origin. Most of these diseases appear to represent the childhood counterpart of diseases observed in adults. The most notable exceptions are represented by early-onset, ANA-positive arthritis, which is specific to childhood, and by the much higher frequency in children of systemic JIA which is considered the equivalent of adult-onset Still's disease. These two diseases present peculiar clinical and immunological aspects.",

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AB - Juvenile idiopathic arthritis (JIA) is not a disease, but an exclusion diagnosis that gathers together all forms of arthritis that begin before the age of 16 years, persist for more than 6 weeks, and are of unknown origin. Most of these diseases appear to represent the childhood counterpart of diseases observed in adults. The most notable exceptions are represented by early-onset, ANA-positive arthritis, which is specific to childhood, and by the much higher frequency in children of systemic JIA which is considered the equivalent of adult-onset Still's disease. These two diseases present peculiar clinical and immunological aspects.

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ER -

Juvenile Idiopathic Arthritis

Abstract

Keywords

ASJC Scopus subject areas

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