TY - JOUR
T1 - Joint statement of the European Association for the Study of Obesity and the European Society of Hypertension
T2 - Obesity and heart failure
AU - Jordan, Jens
AU - Toplak, Hermann
AU - Grassi, Guido
AU - Yumuk, Volkan
AU - Kotsis, Vasilios
AU - Engeli, Stefan
AU - Cuspidi, Cesare
AU - Nilsson, Peter M.
AU - Finer, Nick
AU - Doehner, Wolfram
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Obese individuals are more likely to develop heart failure. Yet, once heart failure is established, the impact of overweight and obesity on prognosis and survival is unclear. The purpose of this joint scientific statement of the European Association for the Study of Obesity and the European Society of Hypertension is to provide an overview on the current scientific literature on obesity and heart failure in terms of prognosis, mechanisms, and clinical management implications. Moreover, the document identifies open questions that ought to be addressed. The need for more tailored weight management recommendations in heart failure will be emphasized and, in line with the emerging evidence, aims to distinguish between primary disease and secondary outcome prevention. In the primary prevention of heart failure, it appears prudent advising obese individuals to lose or achieve a healthy body weight, especially in those with risk factors such as hypertension or type 2 diabetes. However, there is no evidence from clinical trials to guide weight management in overweight or obese patients with established heart failure. Prospective clinical trials are strongly encouraged.
AB - Obese individuals are more likely to develop heart failure. Yet, once heart failure is established, the impact of overweight and obesity on prognosis and survival is unclear. The purpose of this joint scientific statement of the European Association for the Study of Obesity and the European Society of Hypertension is to provide an overview on the current scientific literature on obesity and heart failure in terms of prognosis, mechanisms, and clinical management implications. Moreover, the document identifies open questions that ought to be addressed. The need for more tailored weight management recommendations in heart failure will be emphasized and, in line with the emerging evidence, aims to distinguish between primary disease and secondary outcome prevention. In the primary prevention of heart failure, it appears prudent advising obese individuals to lose or achieve a healthy body weight, especially in those with risk factors such as hypertension or type 2 diabetes. However, there is no evidence from clinical trials to guide weight management in overweight or obese patients with established heart failure. Prospective clinical trials are strongly encouraged.
KW - heart failure
KW - hypertension
KW - neurohumoral
KW - obesity
KW - obesity paradox
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U2 - 10.1097/HJH.0000000000001013
DO - 10.1097/HJH.0000000000001013
M3 - Review article
AN - SCOPUS:84982883832
SN - 0263-6352
VL - 34
SP - 1678
EP - 1688
JO - Journal of Hypertension
JF - Journal of Hypertension
IS - 9
ER -