Is the treatment of keloid scars still a challenge in 2006?

Francesca De Lorenzi, Hanneke J P Tielemans, René R W J Van Der Hulst, Rose Rhemrev, Fred H M Nieman, Ludy C H W Lutgens, Willy D. Boeckx

Research output: Contribution to journalArticlepeer-review


BACKGROUND: Several options are described to treat keloid scars, none of them being 100% successful. Radiotherapy is suggested to have the most significant effect on recurrence rate. OBJECTIVES: The aim of the study is to confirm the effectiveness of iridium brachytherapy combined with surgery and to evaluate patient satisfaction. PATIENTS AND METHODS: We retrospectively enrolled 24 patients with 30 keloids, treated by surgical excision and iridium 192 high-dose-rate (HDR) brachytherapy. RESULTS:: We observed a significant difference in scar thickness before and after the treatment (P <0.001). With regard to patient satisfaction and complaints, 79.1% of them had no pain and irritation after treatment, 79.2% of patients would recommend this treatment to other patients, and 87.5% would undergo this treatment again if necessary. CONCLUSIONS: Our results confirm the effectiveness of surgical keloid excision followed by HDR brachytherapy in primary treatment or if other alternative methods have failed.

Original languageEnglish
Pages (from-to)186-192
Number of pages7
JournalAnnals of Plastic Surgery
Issue number2
Publication statusPublished - Feb 2007


  • Brachytherapy
  • Keloid scar
  • Surgical excision

ASJC Scopus subject areas

  • Surgery


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