The expression of involucrin was studied in a group of skin neoplasms, mostly of adnexal origin. As happens with other types of epithelial tumours, involucrin was detected in the most differentiated areas (presenting a squamoid or ductal differentiation). No reactivity was observed in non-epithelial skin tumours. These results suggest that involucrin is a specific marker for epithelial and adnexal differentiation of skin tumours and may thus be a useful aid in histopathologic diagnosis and classification of neoplasms.
|Number of pages||14|
|Journal||Virchows Archiv A Pathological Anatomy and Histopathology|
|Publication status||Published - Sept 1986|
- Adnexal skin tumours
ASJC Scopus subject areas
- Pathology and Forensic Medicine