Abstract
The expression of involucrin was studied in a group of skin neoplasms, mostly of adnexal origin. As happens with other types of epithelial tumours, involucrin was detected in the most differentiated areas (presenting a squamoid or ductal differentiation). No reactivity was observed in non-epithelial skin tumours. These results suggest that involucrin is a specific marker for epithelial and adnexal differentiation of skin tumours and may thus be a useful aid in histopathologic diagnosis and classification of neoplasms.
Original language | English |
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Pages (from-to) | 527-540 |
Number of pages | 14 |
Journal | Virchows Archiv A Pathological Anatomy and Histopathology |
Volume | 408 |
Issue number | 5 |
DOIs | |
Publication status | Published - Sept 1986 |
Keywords
- Adnexal skin tumours
- Involucrin
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Anatomy