Involucrin expression in adnexal skin tumours - An immunohistological study

J. Kanitakis, G. Zambruno, J. Viac, J. Thivolet

Research output: Contribution to journalArticlepeer-review


The expression of involucrin was studied in a group of skin neoplasms, mostly of adnexal origin. As happens with other types of epithelial tumours, involucrin was detected in the most differentiated areas (presenting a squamoid or ductal differentiation). No reactivity was observed in non-epithelial skin tumours. These results suggest that involucrin is a specific marker for epithelial and adnexal differentiation of skin tumours and may thus be a useful aid in histopathologic diagnosis and classification of neoplasms.

Original languageEnglish
Pages (from-to)527-540
Number of pages14
JournalVirchows Archiv A Pathological Anatomy and Histopathology
Issue number5
Publication statusPublished - Sept 1986


  • Adnexal skin tumours
  • Involucrin

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Anatomy


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