Inverse association between free insulin-like growth factor-1 and isovolumic relaxation in arterial systemic hypertension

Maurizio Galderisi; Giovanni Vitale; Giovanni Lupoli; Michelangela Barbieri; Gina Varricchio; Carlo Carella; Oreste De Divitiis; Giuseppe Paolisso

Inverse association between free insulin-like growth factor-1 and isovolumic relaxation in arterial systemic hypertension

Maurizio Galderisi, Giovanni Vitale, Giovanni Lupoli, Michelangela Barbieri, Gina Varricchio, Carlo Carella, Oreste De Divitiis, Giuseppe Paolisso

Fondazione Istituto Auxologico Italiano

Research output: Contribution to journal › Article › peer-review

Abstract

Several trials have suggested that insulin-like growth factor-1 (IGF-1) may have a pathophysiological role in the development of arterial essential hypertension. To verify the possible association of IGF-1 with left ventricular morphological and functional echocardiographic parameters in hypertension, we studied 40 male patients with newly diagnosed hypertension and 15 normotensive control subjects. Doppler echocardiography was performed and circulating free IGF-1 levels were determined in all subjects. Circulating free IGF-1 levels were higher in hypertensives than in control subjects (P

Original language	English
Pages (from-to)	840-845
Number of pages	6
Journal	Hypertension
Volume	38
Issue number	4
Publication status	Published - 2001

Keywords

Diastole
Echocardiography
Hypertension, arterial
Insulin growth factor
Relaxation

ASJC Scopus subject areas

Internal Medicine

Cite this

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abstract = "Several trials have suggested that insulin-like growth factor-1 (IGF-1) may have a pathophysiological role in the development of arterial essential hypertension. To verify the possible association of IGF-1 with left ventricular morphological and functional echocardiographic parameters in hypertension, we studied 40 male patients with newly diagnosed hypertension and 15 normotensive control subjects. Doppler echocardiography was performed and circulating free IGF-1 levels were determined in all subjects. Circulating free IGF-1 levels were higher in hypertensives than in control subjects (P",

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AU - Galderisi, Maurizio

AU - Vitale, Giovanni

AU - Lupoli, Giovanni

AU - Barbieri, Michelangela

AU - Varricchio, Gina

AU - Carella, Carlo

AU - De Divitiis, Oreste

AU - Paolisso, Giuseppe

PY - 2001

Y1 - 2001

N2 - Several trials have suggested that insulin-like growth factor-1 (IGF-1) may have a pathophysiological role in the development of arterial essential hypertension. To verify the possible association of IGF-1 with left ventricular morphological and functional echocardiographic parameters in hypertension, we studied 40 male patients with newly diagnosed hypertension and 15 normotensive control subjects. Doppler echocardiography was performed and circulating free IGF-1 levels were determined in all subjects. Circulating free IGF-1 levels were higher in hypertensives than in control subjects (P

AB - Several trials have suggested that insulin-like growth factor-1 (IGF-1) may have a pathophysiological role in the development of arterial essential hypertension. To verify the possible association of IGF-1 with left ventricular morphological and functional echocardiographic parameters in hypertension, we studied 40 male patients with newly diagnosed hypertension and 15 normotensive control subjects. Doppler echocardiography was performed and circulating free IGF-1 levels were determined in all subjects. Circulating free IGF-1 levels were higher in hypertensives than in control subjects (P

KW - Diastole

KW - Echocardiography

KW - Hypertension, arterial

KW - Insulin growth factor

KW - Relaxation

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Inverse association between free insulin-like growth factor-1 and isovolumic relaxation in arterial systemic hypertension

Abstract

Keywords

ASJC Scopus subject areas

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