TY - JOUR
T1 - Intravitreal bevacizumab for macular complications from retinal arterial macroaneurysms
AU - Pichi, Francesco
AU - Morara, Mariachiara
AU - Torrazza, Carlo
AU - Manzi, Gianluigi
AU - Alkabes, Micol
AU - Balducci, Nicole
AU - Vitale, Lucia
AU - Lembo, Andrea
AU - Ciardella, Antonio P.
AU - Nucci, Paolo
PY - 2013/2
Y1 - 2013/2
N2 - Purpose: To evaluate the anatomic and functional results of the treatment with intravitreal bevacizumab in complicated retinal arterial macroaneurysm (RAM). Design: A multicenter interventional, prospective, nonrandomized study. Methods: Thirty-eight macroaneurysms of 37 patients with foveal complications were evaluated. All patients underwent a comprehensive ophthalmologic examination, fluorescein angiography (FA), and spectral-domain optical coherence tomography (SD OCT) examination. Each patient underwent 3 monthly injections of bevacizumab 1.25 mg/0.05 mL; 3 follow-up visits were planned at week 2, 6, and 12. Results: Both best-corrected visual acuity (BCVA), expressed in logarithm of minimal angle of resolution (logMAR), and central retinal thickness (CRT) significantly improved during the follow-up visits (0.57 ± 0.21 vs 0.41 ± 0.15 vs 0.23 ± 0.13 vs 0.09 ± 0.10 and 520.38 ± 191.05 vs 396.24 ± 136.18 vs 283.86 ± 71.87 vs 214.84 ± 26.86, respectively, Friedman test P
AB - Purpose: To evaluate the anatomic and functional results of the treatment with intravitreal bevacizumab in complicated retinal arterial macroaneurysm (RAM). Design: A multicenter interventional, prospective, nonrandomized study. Methods: Thirty-eight macroaneurysms of 37 patients with foveal complications were evaluated. All patients underwent a comprehensive ophthalmologic examination, fluorescein angiography (FA), and spectral-domain optical coherence tomography (SD OCT) examination. Each patient underwent 3 monthly injections of bevacizumab 1.25 mg/0.05 mL; 3 follow-up visits were planned at week 2, 6, and 12. Results: Both best-corrected visual acuity (BCVA), expressed in logarithm of minimal angle of resolution (logMAR), and central retinal thickness (CRT) significantly improved during the follow-up visits (0.57 ± 0.21 vs 0.41 ± 0.15 vs 0.23 ± 0.13 vs 0.09 ± 0.10 and 520.38 ± 191.05 vs 396.24 ± 136.18 vs 283.86 ± 71.87 vs 214.84 ± 26.86, respectively, Friedman test P
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U2 - 10.1016/j.ajo.2012.07.029
DO - 10.1016/j.ajo.2012.07.029
M3 - Article
C2 - 23111179
AN - SCOPUS:84872330755
SN - 0002-9394
VL - 155
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 2
ER -