TY - JOUR
T1 - Intermittent and persistent allergic rhinitis and association with asthma in children
AU - Ciprandi, Giorgio
AU - Cadario, G.
AU - Di Gioacchino, M.
AU - Tosca, M. A.
AU - Bernardini, R.
AU - Marseglia, G. L.
AU - Gangemi, S.
AU - Isola, S.
AU - Marengo, F.
AU - Minelli, M.
AU - Ricciardi, L.
AU - Ridolo, E.
AU - Valle, C.
AU - Verini, M.
AU - Borrelli, P.
AU - Varin, E.
AU - Sambugaro, R.
AU - Puccinelli, P.
AU - Incorvaia, C.
AU - Russello, M.
AU - Milioni, M.
AU - Boccardo, R.
AU - Piergentili, E.
AU - Di Rienzo, A.
AU - Frati, F.
PY - 2008/9
Y1 - 2008/9
N2 - The natural history of allergic rhinitis (AR) is commonly characterized by worsening of symptom severity, frequent comorbidity with asthma, and polysensitization to aeroallergens. The polysensitization phenomenon starts in early childhood. AR classification has been recently revised, and some studies investigated the new types: intermittent (IAR) and persistent (PER) AR. However, no study has been carried out on children regarding this issue. This preliminary study was performed on a large cohort of children with allergic rhinitis to evaluate the type and severity of rhinitis and its possible association with asthma, including severity grade. One hundred and thirty-nine children (86 males, 53 females, mean age 11.8 years, range 3.5-17.7 years) with allergic rhinitis were prospectively and consecutively evaluated. Seventy-one children had rhinitis alone and 68 had rhinitis associated with asthma. Forty children had IAR, 30 of whom with moderate-severe grade. Ninety-nine children had PER, 65 of whom had moderate-severe grade. The Severity of AR was not associated with asthma presence (Fisher X2 = 0.5765; Prob.=0.9018). Regarding asthma severity, 30 children had the intermittent form, whereas 38 had the persistent form: 15 mild, 22 moderate, and 1 severe. This study provides the first evidence concerning the ARIA classification in children, partially confirming findings obtained in adulthood.
AB - The natural history of allergic rhinitis (AR) is commonly characterized by worsening of symptom severity, frequent comorbidity with asthma, and polysensitization to aeroallergens. The polysensitization phenomenon starts in early childhood. AR classification has been recently revised, and some studies investigated the new types: intermittent (IAR) and persistent (PER) AR. However, no study has been carried out on children regarding this issue. This preliminary study was performed on a large cohort of children with allergic rhinitis to evaluate the type and severity of rhinitis and its possible association with asthma, including severity grade. One hundred and thirty-nine children (86 males, 53 females, mean age 11.8 years, range 3.5-17.7 years) with allergic rhinitis were prospectively and consecutively evaluated. Seventy-one children had rhinitis alone and 68 had rhinitis associated with asthma. Forty children had IAR, 30 of whom with moderate-severe grade. Ninety-nine children had PER, 65 of whom had moderate-severe grade. The Severity of AR was not associated with asthma presence (Fisher X2 = 0.5765; Prob.=0.9018). Regarding asthma severity, 30 children had the intermittent form, whereas 38 had the persistent form: 15 mild, 22 moderate, and 1 severe. This study provides the first evidence concerning the ARIA classification in children, partially confirming findings obtained in adulthood.
KW - Allergic rhinitis classification and severity
KW - ARIA
KW - Asthma
KW - Children
UR - http://www.scopus.com/inward/record.url?scp=58149493035&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=58149493035&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:58149493035
SN - 1721-727X
VL - 6
SP - 123
EP - 128
JO - European Journal of Inflammation
JF - European Journal of Inflammation
IS - 3
ER -