Intermediate versus hard end points in clinical trials on hypertension

Guido Grassi

Research output: Contribution to journalArticlepeer-review


The main features of randomized clinical trials performed in the field of hypertension treatment are reviewed, based either on the evaluation of clinical events or on the assessment of surrogate outcome measures. The advantages, limitations, and clinical relevance of each approach are highlighted.

Original languageEnglish
Pages (from-to)294-297
Number of pages4
JournalCurrent Hypertension Reports
Issue number4
Publication statusPublished - Aug 2005

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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