Interarm blood pressure differences predict target organ damage in type 2 diabetes

Francesco Spannella, Federico Giulietti, Massimiliano Fedecostante, Maddalena Ricci, Paolo Balietti, Guido Cocci, Laura Landi, Anna Rita Bonfigli, Massimo Boemi, Emma Espinosa, Riccardo Sarzani

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Patients with type 2 diabetes mellitus are at high risk for atherosclerotic disease, and proper blood pressure measurement is mandatory. The authors examined the prevalence of an interarm difference (IAD) in blood pressure and its association with cardiovascular risk factors and organ damage (nephropathy, retinopathy, left ventricular hypertrophy, and vascular damage) in a large diabetic population. A total of 800 consecutive patients with type 2 diabetes mellitus were evaluated with an automated simultaneous bilateral device (men: 422 [52.8%]; mean age: 68.1±12.2 years). Diabetic patients with systolic IAD ≥5 and systolic IAD ≥10 mm Hg showed an increased risk of having vascular damage (adjusted odds ratios: 1.73 and 2.49, respectively) and higher pulse pressure. IAD is highly prevalent in patients with diabetes, is associated with vascular damage, even for IAD ≥5 mm Hg, and should be accurately obtained to avoid underdiagnosis and undertreatment of hypertension.

Original languageEnglish
JournalJournal of clinical hypertension (Greenwich, Conn.)
Publication statusE-pub ahead of print - Dec 27 2016


  • Journal Article


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