Integrating augmented reality tools in breast cancer related lymphedema prognostication and diagnosis

Marco Invernizzi; Letterio Runza; Alessandro De Sire; Lorenzo Lippi; Concetta Blundo; Donatella Gambini; Renzo Boldorini; Stefano Ferrero; Nicola Fusco

doi:10.3791/60093

Integrating augmented reality tools in breast cancer related lymphedema prognostication and diagnosis

Marco Invernizzi, Letterio Runza, Alessandro De Sire, Lorenzo Lippi, Concetta Blundo, Donatella Gambini, Renzo Boldorini, Stefano Ferrero, Nicola Fusco

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

Breast cancer related lymphedema (BCRL) is a detrimental condition characterized by fluid accumulation in the upper limb in breast cancer patients subjected to axillary surgery and/or radiations. Its etiology is multifactorial and include also tumor-specific pathological features, such as lymphovascular invasion (LVI) and extranodal extension (ENE). To date, no widely employed guidelines for the early diagnosis of BCRL are available. Here, we illustrate a protocol for a digitally assisted BCRL assessment using a 3D laser scanner (3DLS) and a tablet computer. It has been specifically optimized in a discovery cohort of high-risk breast cancer patients. This study provides a proof-of-principle that augmented reality tools, such as 3DLS, can be incorporated into the clinical workup of BCRL to allow for a precise, reproducible, reliable, and cheap diagnosis.

Original language	English
Article number	e60093
Journal	Journal of Visualized Experiments
Volume	2020
Issue number	156
DOIs	https://doi.org/10.3791/60093
Publication status	Published - Feb 2020

Keywords

3D laser scanner
Axillary lymph nodes dissection
Breast cancer
Breast cancer related lymphedema
Extranodal extension
Issue 156
Lymphovascular invasion
Medicine

ASJC Scopus subject areas

Neuroscience(all)
Chemical Engineering(all)
Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)

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10.3791/60093

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title = "Integrating augmented reality tools in breast cancer related lymphedema prognostication and diagnosis",

abstract = "Breast cancer related lymphedema (BCRL) is a detrimental condition characterized by fluid accumulation in the upper limb in breast cancer patients subjected to axillary surgery and/or radiations. Its etiology is multifactorial and include also tumor-specific pathological features, such as lymphovascular invasion (LVI) and extranodal extension (ENE). To date, no widely employed guidelines for the early diagnosis of BCRL are available. Here, we illustrate a protocol for a digitally assisted BCRL assessment using a 3D laser scanner (3DLS) and a tablet computer. It has been specifically optimized in a discovery cohort of high-risk breast cancer patients. This study provides a proof-of-principle that augmented reality tools, such as 3DLS, can be incorporated into the clinical workup of BCRL to allow for a precise, reproducible, reliable, and cheap diagnosis.",

keywords = "3D laser scanner, Axillary lymph nodes dissection, Breast cancer, Breast cancer related lymphedema, Extranodal extension, Issue 156, Lymphovascular invasion, Medicine",

author = "Marco Invernizzi and Letterio Runza and {De Sire}, Alessandro and Lorenzo Lippi and Concetta Blundo and Donatella Gambini and Renzo Boldorini and Stefano Ferrero and Nicola Fusco",

year = "2020",

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doi = "10.3791/60093",

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AU - Invernizzi, Marco

AU - Runza, Letterio

AU - De Sire, Alessandro

AU - Lippi, Lorenzo

AU - Blundo, Concetta

AU - Gambini, Donatella

AU - Boldorini, Renzo

AU - Ferrero, Stefano

AU - Fusco, Nicola

PY - 2020/2

Y1 - 2020/2

N2 - Breast cancer related lymphedema (BCRL) is a detrimental condition characterized by fluid accumulation in the upper limb in breast cancer patients subjected to axillary surgery and/or radiations. Its etiology is multifactorial and include also tumor-specific pathological features, such as lymphovascular invasion (LVI) and extranodal extension (ENE). To date, no widely employed guidelines for the early diagnosis of BCRL are available. Here, we illustrate a protocol for a digitally assisted BCRL assessment using a 3D laser scanner (3DLS) and a tablet computer. It has been specifically optimized in a discovery cohort of high-risk breast cancer patients. This study provides a proof-of-principle that augmented reality tools, such as 3DLS, can be incorporated into the clinical workup of BCRL to allow for a precise, reproducible, reliable, and cheap diagnosis.

AB - Breast cancer related lymphedema (BCRL) is a detrimental condition characterized by fluid accumulation in the upper limb in breast cancer patients subjected to axillary surgery and/or radiations. Its etiology is multifactorial and include also tumor-specific pathological features, such as lymphovascular invasion (LVI) and extranodal extension (ENE). To date, no widely employed guidelines for the early diagnosis of BCRL are available. Here, we illustrate a protocol for a digitally assisted BCRL assessment using a 3D laser scanner (3DLS) and a tablet computer. It has been specifically optimized in a discovery cohort of high-risk breast cancer patients. This study provides a proof-of-principle that augmented reality tools, such as 3DLS, can be incorporated into the clinical workup of BCRL to allow for a precise, reproducible, reliable, and cheap diagnosis.

KW - 3D laser scanner

KW - Axillary lymph nodes dissection

KW - Breast cancer

KW - Breast cancer related lymphedema

KW - Extranodal extension

KW - Issue 156

KW - Lymphovascular invasion

KW - Medicine

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ER -

Integrating augmented reality tools in breast cancer related lymphedema prognostication and diagnosis

Abstract

Keywords

ASJC Scopus subject areas

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