Influence of QRS prolongation on the natural history of CHF

Luigi Padeletti; Marzia Giaccardi; Federico Turreni; Nicola Musilli; Andrea Colella; Paolo Pieragnoli; Antonio Michelucci; Giuseppe Ricciardi; Maria Cristina Porciani

doi:10.1016/j.ehjsup.2004.05.023

Influence of QRS prolongation on the natural history of CHF

Luigi Padeletti, Marzia Giaccardi, Federico Turreni, Nicola Musilli, Andrea Colella, Paolo Pieragnoli, Antonio Michelucci, Giuseppe Ricciardi, Maria Cristina Porciani

IRCCS Multimedica

Research output: Contribution to journal › Article › peer-review

Abstract

Aims To evaluate the influence of QRS prolongation on the natural history of chronic heart failure (CHF). Methods The results of several studies carried out from 1951 to 2003 were analysed. Results (a) Isolated left bundle branch block (LBBB) is associated with an increased risk of developing cardiovascular disease and increased cardiac mortality; (b) investigations on the effect of right bundle branch block (RBBB) on mortality have yelded conflicting results; (c) the effects of the association of LBBB with left axis deviation (LAD) on further LV function deterioration remain controversial; (d) LBBB in CHF is associated with a significantly higher all-cause and sudden cardiac death mortality. Conclusions LBBB is unequivocably associated with greater disease severity and mortality in patients with CHF.

Original language	English
Journal	European Heart Journal, Supplement
Volume	6
Issue number	D
DOIs	https://doi.org/10.1016/j.ehjsup.2004.05.023
Publication status	Published - Aug 2004

Keywords

Bundle branch block
Heart failure
Mortality
QRS duration

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.ehjsup.2004.05.023

Cite this

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title = "Influence of QRS prolongation on the natural history of CHF",

abstract = "Aims To evaluate the influence of QRS prolongation on the natural history of chronic heart failure (CHF). Methods The results of several studies carried out from 1951 to 2003 were analysed. Results (a) Isolated left bundle branch block (LBBB) is associated with an increased risk of developing cardiovascular disease and increased cardiac mortality; (b) investigations on the effect of right bundle branch block (RBBB) on mortality have yelded conflicting results; (c) the effects of the association of LBBB with left axis deviation (LAD) on further LV function deterioration remain controversial; (d) LBBB in CHF is associated with a significantly higher all-cause and sudden cardiac death mortality. Conclusions LBBB is unequivocably associated with greater disease severity and mortality in patients with CHF.",

keywords = "Bundle branch block, Heart failure, Mortality, QRS duration",

author = "Luigi Padeletti and Marzia Giaccardi and Federico Turreni and Nicola Musilli and Andrea Colella and Paolo Pieragnoli and Antonio Michelucci and Giuseppe Ricciardi and {Cristina Porciani}, Maria",

year = "2004",

month = aug,

doi = "10.1016/j.ehjsup.2004.05.023",

language = "English",

volume = "6",

journal = "European Heart Journal, Supplement",

issn = "1520-765X",

publisher = "Oxford University Press",

number = "D",

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T1 - Influence of QRS prolongation on the natural history of CHF

AU - Padeletti, Luigi

AU - Giaccardi, Marzia

AU - Turreni, Federico

AU - Musilli, Nicola

AU - Colella, Andrea

AU - Pieragnoli, Paolo

AU - Michelucci, Antonio

AU - Ricciardi, Giuseppe

AU - Cristina Porciani, Maria

PY - 2004/8

Y1 - 2004/8

N2 - Aims To evaluate the influence of QRS prolongation on the natural history of chronic heart failure (CHF). Methods The results of several studies carried out from 1951 to 2003 were analysed. Results (a) Isolated left bundle branch block (LBBB) is associated with an increased risk of developing cardiovascular disease and increased cardiac mortality; (b) investigations on the effect of right bundle branch block (RBBB) on mortality have yelded conflicting results; (c) the effects of the association of LBBB with left axis deviation (LAD) on further LV function deterioration remain controversial; (d) LBBB in CHF is associated with a significantly higher all-cause and sudden cardiac death mortality. Conclusions LBBB is unequivocably associated with greater disease severity and mortality in patients with CHF.

AB - Aims To evaluate the influence of QRS prolongation on the natural history of chronic heart failure (CHF). Methods The results of several studies carried out from 1951 to 2003 were analysed. Results (a) Isolated left bundle branch block (LBBB) is associated with an increased risk of developing cardiovascular disease and increased cardiac mortality; (b) investigations on the effect of right bundle branch block (RBBB) on mortality have yelded conflicting results; (c) the effects of the association of LBBB with left axis deviation (LAD) on further LV function deterioration remain controversial; (d) LBBB in CHF is associated with a significantly higher all-cause and sudden cardiac death mortality. Conclusions LBBB is unequivocably associated with greater disease severity and mortality in patients with CHF.

KW - Bundle branch block

KW - Heart failure

KW - Mortality

KW - QRS duration

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JO - European Heart Journal, Supplement

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Influence of QRS prolongation on the natural history of CHF

Abstract

Keywords

ASJC Scopus subject areas

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