TY - JOUR
T1 - Independent prognostic value of functional mitral regurgitation in patients with heart failure. A quantitative analysis of 1256 patients with ischaemic and non-ischaemic dilated cardiomyopathy
AU - Rossi, Andrea
AU - Dini, Frank L.
AU - Faggiano, Pompilio
AU - Agricola, Eustachio
AU - Cicoira, Mariantonietta
AU - Frattini, Silvia
AU - Simioniuc, Anca
AU - Gullace, Mariangela
AU - Ghio, Stefano
AU - Enriquez-Sarano, Maurice
AU - Temporelli, Pier Luigi
PY - 2011/10
Y1 - 2011/10
N2 - Background: Functional mitral regurgitation (FMR) is a common finding in patients with heart failure (HF), but its effect on outcome is still uncertain, mainly because in previous studies sample sizes were relatively small and semiquantitative methods for FMR grading were used. Objective: To evaluate the prognostic value of FMR in patients with HF. Methods and results: Patients with HF due to ischaemic and non-ischaemic dilated cardiomyopathy (DCM) were retrospectively recruited. The clinical end point was a composite of all-cause mortality and hospitalisation for worsening HF. FMR was quantitatively determined by measuring vena contracta (VC) or effective regurgitant orifice (ERO) or regurgitant volume (RV). Severe FMR was defined as ERO >0.2 cm 2 or RV >30 ml or VC >0.4 cm. Restrictive mitral filling pattern (RMP) was defined as E-wave deceleration time
AB - Background: Functional mitral regurgitation (FMR) is a common finding in patients with heart failure (HF), but its effect on outcome is still uncertain, mainly because in previous studies sample sizes were relatively small and semiquantitative methods for FMR grading were used. Objective: To evaluate the prognostic value of FMR in patients with HF. Methods and results: Patients with HF due to ischaemic and non-ischaemic dilated cardiomyopathy (DCM) were retrospectively recruited. The clinical end point was a composite of all-cause mortality and hospitalisation for worsening HF. FMR was quantitatively determined by measuring vena contracta (VC) or effective regurgitant orifice (ERO) or regurgitant volume (RV). Severe FMR was defined as ERO >0.2 cm 2 or RV >30 ml or VC >0.4 cm. Restrictive mitral filling pattern (RMP) was defined as E-wave deceleration time
UR - http://www.scopus.com/inward/record.url?scp=80053186563&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80053186563&partnerID=8YFLogxK
U2 - 10.1136/hrt.2011.225789
DO - 10.1136/hrt.2011.225789
M3 - Article
C2 - 21807656
AN - SCOPUS:80053186563
SN - 1355-6037
VL - 97
SP - 1675
EP - 1680
JO - Heart
JF - Heart
IS - 20
ER -