Increased coronary tone in exertional angina: The beneficial effects of calcium antagonists

Giuseppe Specchia; Diego Ardissino; Stefano Ghio; Paolo Barberis; Maria Luigia Colombo; Stefano De Servi

doi:10.1007/BF02018288

Increased coronary tone in exertional angina: The beneficial effects of calcium antagonists

Giuseppe Specchia, Diego Ardissino, Stefano Ghio, Paolo Barberis, Maria Luigia Colombo, Stefano De Servi

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Coronary vasoconstriction may play a relevant role in the pathogenesis of exercise-induced myocardial ischemia, not only in patients with Prinzmetal's angina, but also in patients with chronic stable angina. In these patients the use of calcium antagonists, namely, dihydropyridine derivatives, may be beneficial. Hyperventilation is a simple and sensitive test to discriminate patients with effort angina who will improve their exercise capacity after administration of these drugs.

Original language	English
Pages (from-to)	893-897
Number of pages	5
Journal	Cardiovascular Drugs and Therapy
Volume	4
Issue number	5 Supplement
DOIs	https://doi.org/10.1007/BF02018288
Publication status	Published - Sept 1990

Keywords

coronary vasoconstriction
exercise-induced angina
hyperventilation

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Cardiology and Cardiovascular Medicine

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10.1007/BF02018288

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AU - De Servi, Stefano

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AB - Coronary vasoconstriction may play a relevant role in the pathogenesis of exercise-induced myocardial ischemia, not only in patients with Prinzmetal's angina, but also in patients with chronic stable angina. In these patients the use of calcium antagonists, namely, dihydropyridine derivatives, may be beneficial. Hyperventilation is a simple and sensitive test to discriminate patients with effort angina who will improve their exercise capacity after administration of these drugs.

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Increased coronary tone in exertional angina: The beneficial effects of calcium antagonists

Abstract

Keywords

ASJC Scopus subject areas

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