INCREASED BLINKING MAY BE A PRECURSOR OF BLEPHAROSPASM: A LONGITUDINAL STUDY

Antonella Conte; Gina Ferrazzano; Giovanni Defazio; Giovanni Fabbrini; Mark Hallett; Alfredo Berardelli

doi:10.1002/mdc3.12499

INCREASED BLINKING MAY BE A PRECURSOR OF BLEPHAROSPASM: A LONGITUDINAL STUDY

Antonella Conte, Gina Ferrazzano, Giovanni Defazio, Giovanni Fabbrini, Mark Hallett, Alfredo Berardelli

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Abstract

OBJECTIVE: The aim of this five-year longitudinal study was to investigate whether patients with increased blinking develop orbicularis oculi muscle spasms.

METHODS: Eleven patients who initially manifested increased blinking alone were clinically and neurophysiologically re-evaluated five years later.

RESULTS: By the five-year follow-up assessment, nine of the 11 patients had developed orbicularis oculi muscle spasms. The blink reflex recovery cycle became abnormal whereas somatosensory temporal discrimination, already abnormal at the first evaluation, did not significantly change.

CONCLUSIONS: Our longitudinal study demonstrates that increased blinking may precede blepharospasm and that an abnormal blink reflex recovery cycle reflects the development of orbicularis oculi muscle spasms.

Original language	English
Pages (from-to)	733-736
Number of pages	4
Journal	Movement Disorders Clinical Practice
Volume	4
Issue number	5
DOIs	https://doi.org/10.1002/mdc3.12499
Publication status	Published - Oct 31 2017

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abstract = "OBJECTIVE: The aim of this five-year longitudinal study was to investigate whether patients with increased blinking develop orbicularis oculi muscle spasms.METHODS: Eleven patients who initially manifested increased blinking alone were clinically and neurophysiologically re-evaluated five years later.RESULTS: By the five-year follow-up assessment, nine of the 11 patients had developed orbicularis oculi muscle spasms. The blink reflex recovery cycle became abnormal whereas somatosensory temporal discrimination, already abnormal at the first evaluation, did not significantly change.CONCLUSIONS: Our longitudinal study demonstrates that increased blinking may precede blepharospasm and that an abnormal blink reflex recovery cycle reflects the development of orbicularis oculi muscle spasms.",

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T1 - INCREASED BLINKING MAY BE A PRECURSOR OF BLEPHAROSPASM

T2 - A LONGITUDINAL STUDY

AU - Conte, Antonella

AU - Ferrazzano, Gina

AU - Defazio, Giovanni

AU - Fabbrini, Giovanni

AU - Hallett, Mark

AU - Berardelli, Alfredo

PY - 2017/10/31

Y1 - 2017/10/31

N2 - OBJECTIVE: The aim of this five-year longitudinal study was to investigate whether patients with increased blinking develop orbicularis oculi muscle spasms.METHODS: Eleven patients who initially manifested increased blinking alone were clinically and neurophysiologically re-evaluated five years later.RESULTS: By the five-year follow-up assessment, nine of the 11 patients had developed orbicularis oculi muscle spasms. The blink reflex recovery cycle became abnormal whereas somatosensory temporal discrimination, already abnormal at the first evaluation, did not significantly change.CONCLUSIONS: Our longitudinal study demonstrates that increased blinking may precede blepharospasm and that an abnormal blink reflex recovery cycle reflects the development of orbicularis oculi muscle spasms.

AB - OBJECTIVE: The aim of this five-year longitudinal study was to investigate whether patients with increased blinking develop orbicularis oculi muscle spasms.METHODS: Eleven patients who initially manifested increased blinking alone were clinically and neurophysiologically re-evaluated five years later.RESULTS: By the five-year follow-up assessment, nine of the 11 patients had developed orbicularis oculi muscle spasms. The blink reflex recovery cycle became abnormal whereas somatosensory temporal discrimination, already abnormal at the first evaluation, did not significantly change.CONCLUSIONS: Our longitudinal study demonstrates that increased blinking may precede blepharospasm and that an abnormal blink reflex recovery cycle reflects the development of orbicularis oculi muscle spasms.

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DO - 10.1002/mdc3.12499

M3 - Article

C2 - 29082270

SN - 2330-1619

VL - 4

SP - 733

EP - 736

JO - Movement Disorders Clinical Practice

JF - Movement Disorders Clinical Practice

IS - 5

ER -

INCREASED BLINKING MAY BE A PRECURSOR OF BLEPHAROSPASM: A LONGITUDINAL STUDY

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